献血者捐献机采血小板对外周血部分实验室检查指标的影响

发布时间：2019-02-17 17:39

【摘要】：目的观察献血者捐献机采血小板后对外周血部分实验室检查指标的影响,以保证血液质量和献血者的健康安全。方法选取2016年3 2016年7月于该站捐献机采血小板(Plt)的献血者70人作为研究对象,分别于捐献血小板前、后检测献血者血常规、血浆蛋白、免疫球蛋白及电解质K~+、Cl~-、Ca~(2+)、Na~+等指标。结果献血者捐献机采血小板后30 min,其Plt水平较献血前显著降低,比较差异有统计学意义(P0.05),白细胞(WBC)、红细胞(RBC)、血红蛋白(Hb)和红细胞比积(Hct)与献血前比较差异无统计学意义(P0.05);献血后14 d上述血常规指标与献血前比较差异无统计学意义(P0.05);捐献机采血小板后30 min血浆中K+、Cl~-、Ca~(2+)、总蛋白(TP)、白蛋白(ALB)及免疫球蛋白(Ig)G、IgA和IgM浓度较献血前显著降低,比较差异有统计学意义(P0.05);献血后14d K~+、Cl~-、Ca~(2+)及IgG、IgA和IgM浓度与献血前比较差异无统计学意义(P0.05),TP、ALB与献血前比较差异有统计学意义(P0.05),献血后30 min和献血后14d Na~+与献血前比较差异均无统计学意义(P0.05)。结论献血者捐献机采血小板后短时间内血小板、血细胞、电解质及血浆蛋白可恢复至正常,对身体影响较小,不会引起电解质紊乱和低蛋白血症。
[Abstract]:Objective to observe the effect of platelet collection from donor blood donors on some laboratory indexes of peripheral blood in order to ensure the blood quality and the health and safety of blood donors. Methods A total of 70 blood donors who collected platelet (Plt) from the donor machine of the station in 3 March 2016 and 7 July 2016 were selected as study subjects. The blood routine examination, plasma protein, immunoglobulin and electrolyte K ~, Cl~-, were detected before and after platelet donation. Ca~ (2), Na~ and so on. Results the level of Plt in blood donors was significantly lower than that before blood donation 30 min, after platelet collection (P0.05). The level of (RBC), in leukocyte (WBC), erythrocytes was significantly lower than that before blood donation (P0.05). There was no significant difference between hemoglobin (Hb) and hematocrit (Hct) before blood donation (P0.05). On the 14th day after blood donation, there was no significant difference between the above indexes of blood routine and that before blood donation (P0.05). The concentrations of K, Cl~-,Ca~ (2), total protein (TP), albumin (ALB) and immunoglobulin (Ig) Gluten IgA and IgM were significantly lower than those before blood donation 30 min after platelet donation (P0.05). On the 14th day after blood donation, there was no significant difference in K ~, Cl~-,Ca~ (2), IgG,IgA and IgM concentrations between before and after blood donation (P0.05), but there was a significant difference between TP,ALB and blood donors (P0.05). 30 min after blood donation and 14 days after blood donation, there was no significant difference in Na~ between before and after blood donation (P0.05). Conclusion platelets, blood cells, electrolytes and plasma proteins can return to normal in a short time after platelet collection by donor blood donors, with little effect on the body and no electrolyte disturbance and hypoproteinemia.
【作者单位】：河南省焦作市中心血站检验科;河南省焦作市妇幼保健院检验科;
【分类号】：R446.11

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