血清降钙素原对不同致病菌感染所致脓毒症的早期诊断及临床研究
发布时间：2019-04-07 15:35
【摘要】：目的探讨血清降钙素原(PCT)、超敏C反应蛋白(hs-CRP)、白细胞计数(WBC)、中性粒细胞百分比(NEU%)在不同致病菌感染所致脓毒症早期诊断的临床价值,为脓毒症患者提供风险评估。方法回顾性分析2013年10月至2015年10月在徐州市中医院重症医学科(ICU)就诊的血流感染致脓毒症117例患者的临床资料,所有患者在抗菌药物使用之前进行血培养,根据血培养结果分为革兰阳性菌(G+菌)组和革兰阴性菌(G-菌)组,所有患者均进行PCT、hs-CRP、WBC、NEU%检测,分析两组患者检测结果的差异,评价PCT与急性生理与慢性健康状况评分系统Ⅱ评分(APACHE-Ⅱ评分)和序贯器官衰竭评分(SOFA评分)的相关性。结果 117例脓毒血症的患者中G+菌组78例,G-菌组39例;与G+菌组比较,G-菌组PCT检测变化明显,差异有统计学意义(P0.05),而hs-CRP、WBC、NEU检测结果变化不大(P0.05);G-菌组血清PCT与SOFA评分呈正相关(r=0.536,P0.05),而与APACHE-Ⅱ评分无相关性(P0.05);G+菌组血清PCT与APACHE-Ⅱ评分、SOFA评分均无相关性(P0.05)。结论 PCT在不同致病菌感染所致脓毒症的早期鉴别诊断和预后监测中有一定价值,且对G-菌更灵敏。
[Abstract]:Objective to investigate the clinical value of serum procalcitonin (PCT), hypersensitive C-reactive protein (hs-CRP) and leukocyte count (WBC), neutrophil percentage (NEU%) in early diagnosis of sepsis caused by different pathogenic bacteria infection. Provides risk assessment for sepsis patients. Methods the clinical data of 117 patients with sepsis caused by blood flow infection were retrospectively analyzed from October 2013 to October 2015 in the Department of critical Medicine of Xuzhou traditional Chinese Medicine Hospital (ICU). All patients were cultured before the use of antibiotics. According to the results of blood culture, they were divided into Gram-positive bacteria (G-bacteria) group and Gram-negative bacteria (G-bacteria) groups. All patients were detected by PCT,hs-CRP,WBC,NEU%, and the difference between the two groups was analyzed. To evaluate the correlation between PCT and acute physiological and chronic health status score 鈪，
本文编号：2454167
[Abstract]:Objective to investigate the clinical value of serum procalcitonin (PCT), hypersensitive C-reactive protein (hs-CRP) and leukocyte count (WBC), neutrophil percentage (NEU%) in early diagnosis of sepsis caused by different pathogenic bacteria infection. Provides risk assessment for sepsis patients. Methods the clinical data of 117 patients with sepsis caused by blood flow infection were retrospectively analyzed from October 2013 to October 2015 in the Department of critical Medicine of Xuzhou traditional Chinese Medicine Hospital (ICU). All patients were cultured before the use of antibiotics. According to the results of blood culture, they were divided into Gram-positive bacteria (G-bacteria) group and Gram-negative bacteria (G-bacteria) groups. All patients were detected by PCT,hs-CRP,WBC,NEU%, and the difference between the two groups was analyzed. To evaluate the correlation between PCT and acute physiological and chronic health status score 鈪，
本文编号：2454167
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