910例成人发热呼吸道症候群住院患者病原谱研究

发布时间：2019-06-02 16:00

【摘要】：目的探讨成人发热呼吸道症候群住院患者病原谱分布情况,为呼吸道感染性疾病的防控提供参考。方法采集2014年3月~2016年2月成都市某医院成人发热呼吸道症候群住院患者的咽拭子或痰液标本,采用RT-PCR和PCR法检测标本中常见的八种呼吸道病毒;用培养法,生化鉴定和微生物全自动鉴定系统,分离鉴定呼吸道感染的细菌和真菌;分析主要病原体和年龄与季节的关系。结果共采集910份标本,病原体检出率为47.58%(433/910);病毒检出率为26.92%(245/910),检出最高的是鼻病毒(9.78%),其冬季感染率高于春,夏,秋季;细菌检出率为13.41%(122/910),肺炎克雷伯菌(6.26%)检出率最高,检出无季节性和年龄差异;真菌检出率为14.51%(132/910),白色念珠菌(11.32%)检出率最高,60岁以上人群感染率高于其他人群(=16.268,P0.001)。结论发热呼吸道症候群住院患者病原体感染率较高,以白色念珠菌,鼻病毒,肺炎克雷伯菌为主,今后应加强病原学的监测,注重病原体在不同人群感染分布和季节性防治。
[Abstract]:Objective to investigate the distribution of etiological spectrum of adult hospitalized patients with febrile respiratory syndrome, and to provide reference for the prevention and control of respiratory infectious diseases. Methods from March 2014 to February 2016, the throat swabs or sputum samples of adult hospitalized patients with febrile respiratory syndrome were collected. Eight kinds of respiratory viruses were detected by RT-PCR and PCR. The bacteria and fungi of respiratory tract infection were isolated and identified by culture method, biochemical identification and microbial automatic identification system, and the relationship between main pathogens and age and season was analyzed. Results A total of 910 specimens were collected, the detection rate of pathogen was 47.58% (433 鈮，

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