基于社会网络分析和共词分析的制药技术领域研究

发布时间：2018-04-19 09:07

本文选题：制药技术 + PubMed　；参考：《现代生物医学进展》2017年02期

【摘要】：目的:深入研究制药技术领域的发展态势。方法:本研究以Pub Med数据库中收录的制药技术领域研究论文为研究对象,采用社会网络分析、共词分析等定量方法,结合药学专业知识的定性分析,从论文数量年度分布、国家/地区分布及合作网络、研究主题等多个角度开展研究。结果:研究发现:第一,全球制药技术领域共有研究论文95381篇,近几年正处于快速发展阶段;第二,论文发表集中在美国、中国和日本等国家;第三,在定量分析的基础上,结合药学专业知识,共得到15个研究主题,包括点击化学、晶型药物、纳米微球药物等。结论:美国在制药技术领域处于主导地位,中国发文量已经具备一定优势,但发文量和国际影响力与美国相比还是存在较大差距;通过对制药技术领域研究主题的深入分析可以全面把握制药技术领域的研究现状和发展态势。
[Abstract]:Objective: to study the development trend of pharmaceutical technology.Methods: taking the pharmaceutical technical research papers included in the Pub Med database as the research object, using the quantitative methods such as social network analysis and coterm analysis, combining with the qualitative analysis of pharmaceutical professional knowledge, the annual distribution of the number of papers was obtained.National / regional distribution and cooperation network, research topics and other perspectives to carry out research.Results: first, there are 95381 research papers in the field of global pharmaceutical technology, which are in the stage of rapid development in recent years; second, the papers are published in the United States, China and Japan; third, on the basis of quantitative analysis,Combined with pharmaceutical expertise, 15 research topics were obtained, including click-chemistry, crystalline drugs, nano-microspheres drugs and so on.Conclusion: the United States is in the leading position in the field of pharmaceutical technology, and China has some advantages, but there is still a big gap between the volume of papers and the international influence compared with the United States.Through the in-depth analysis of the subject of pharmaceutical technology, we can grasp the current situation and development trend of pharmaceutical technology.
【作者单位】：中国医学科学院/北京协和医学院医学信息研究所/图书馆;中国医学科学院/北京协和医学院药物研究所天然药物活性物质与功能国家重点实验室;
【基金】：北京协和医学院协和青年基金中央高校基本科研业务费专项(3332013151) 中国医学科学院/北京协和医学院药物研究所天然药物活性物质与功能国家重点实验室开放课题(GTZK201508)
【分类号】：TQ460;G353.1

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