肺部感染患者支气管肺泡灌洗液培养非发酵菌分析研究

发布时间：2018-01-06 01:36

本文关键词：肺部感染患者支气管肺泡灌洗液培养非发酵菌分析研究　出处：《中华医院感染学杂志》2016年08期 　论文类型：期刊论文

【摘要】：目的探讨肺部感染患者送检支气管肺泡灌洗液培养的非发酵菌感染状况,为肺部感染患者的临床诊治和预防提供参考依据。方法以2012年12月-2014年12月医院临床收治疑似肺部感染患者554例为研究对象,采用支气管肺泡灌洗液培养的方式对患者分泌物进行培养和检测,调查其病原菌检出率、非发酵菌的分布和耐药性,数据采用SPSS 19.0软件进行统计分析。结果 554例患者的分泌物中共分离病原菌198株,检出率为39.40%;198株病原菌中非发酵菌94株占47.47%;铜绿假单胞菌、鲍氏不动杆菌、嗜麦芽寡养单胞菌对亚胺培南、美罗培南、多黏菌素B耐药率较低,均35.00%。结论肺部感染患者的非发酵菌的临床检出率和耐药性均较高,临床工作者应按照药敏结果为指导科学合理用药,从而有效的降低肺部感染发生率。
[Abstract]:Objective to investigate the infection status of non fermentative bacteria from bronchoalveolar lavage fluid culture of patients with pulmonary infection, and provide reference for clinical diagnosis and treatment and prevention of pulmonary infection in patients. Methods in December 2012 -2014 year in December admitted to hospital clinical suspected pulmonary infection in 554 patients as the research object, using bronchoalveolar lavage fluid culture method for culturing and testing with the investigation of secretions, pathogen detection rate, distribution and drug resistance of non fermentative bacteria, SPSS 19 software was used for statistical analysis. Results 554 cases of patients with the secretion of isolated 198 strains of pathogenic bacteria, the detection rate was 39.40%; 198 strains of pathogenic bacteria in 94 strains of non fermentative bacilli accounted for 47.47%; Pseudomonas aeruginosa, abalone Acinetobacter and Stenotrophomonas maltophilia to imipenem, meropenem, polymyxin B resistance rates were 35.00%. the conclusion of non fermentation bacteria of pulmonary infection in patients with clinical The bed detection rate and drug resistance are all high. The clinical workers should guide scientific and rational drug use according to the results of drug sensitivity, which can effectively reduce the incidence of pulmonary infection.

【作者单位】：安阳市人民医院检验科;
【基金】：河南省杰出人才创新基金资助项目(0823092311)
【分类号】：R563.1
【正文快照】： 非发酵菌已经成为感染致病菌中的重要病原菌,在临床实践的过程中,针对病原菌的临床检验对于疾病诊治具有重要临床指导意义。但是,在对患者痰液标本进行送检的过程中,传统常规的方法无法避免口咽菌群对于标本的污染,从而对临床检查结果产生一定的影响[1]。本研究对2012年12月-2

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