老年肺部感染合并心功能不全患者硝酸甘油微泵治疗的安全性与有效性评估

发布时间：2018-01-07 22:31

本文关键词：老年肺部感染合并心功能不全患者硝酸甘油微泵治疗的安全性与有效性评估　出处：《中华医院感染学杂志》2016年14期 　论文类型：期刊论文

【摘要】：目的分析老年肺部感染合并心功能不全患者行硝酸甘油微泵的安全性与有效性,为临床治疗提供参考。方法选取医院2014年2月-2015年4月收治老年肺部感染合并心功能不全患者56例为研究对象,随机为研究组和对照组各28例,对照组患者采取吸氧、控制感染、利尿等治疗,研究组患者在此基础上采取硝酸甘油微泵治疗,分析两组患者治疗效果。结果研究组患者治疗总有效率91.1%,显著高于对照组75.0%(P0.05),治疗前,两组患者PaO_2/FiO_2和CVP差异无统计学意义,治疗后研究组PaO_2/FiO_2(269.34±41.28)显著高于对照组(208.16±49.67)(P0.05),研究组CVP(8.92±2.54)cmH_2O显著低于对照组(11.06±2.25)cmH_2O(P0.05);研究组住院时间、肺部Up音减少时间等显著短于对照组(P0.05),研究组BNP恢复正常时间(2.89±1.28)d显著少于对照组(5.23±1.49)d(P0.05);研究组1例出现头晕症状,调整硝酸甘油剂量后好转。结论老年肺部感染并心功能不全患者治疗中,采用硝酸甘油微泵治疗能够提高治疗效果,不良反应小,具有推广价值。
[Abstract]:Objective to analyze the efficacy and safety of patients with cardiac insufficiency were treated with nitroglycerin micro pump of pulmonary infection in the elderly, to provide reference for clinical treatment. Methods the hospital in February 2014 -2015 year in April from pulmonary infection in the elderly patients with cardiac insufficiency in patients with 56 cases as the research object, randomly into study group and control group 28 cases, control group was treated with oxygen, infection control, diuretic therapy, patients in the study group on the basis of taking nitroglycerin micro pump treatment, analysis of the effect of two groups of patients. The patients in study group the total efficiency of 91.1%, significantly higher than the control group 75% (P0.05), before treatment, the two groups had no statistical significance in patients with PaO_2/FiO_2 and CVP differences in study group after the treatment of PaO_2/FiO_2 (269.34 + 41.28) was significantly higher than the control group (208.16 + 49.67) (P0.05), CVP of the study group (8.92 + 2.54) cmH_2O was significantly lower than the control group (11.06 + 2.25) cmH_2O (P0.05); research Hospitalization time, reduce the time of lung Up was significantly shorter than the control group (P0.05), the study group BNP recovery time (2.89 + 1.28) d significantly less than the control group (5.23 + 1.49) d (P0.05); 1 cases of dizziness symptoms in study group, nitroglycerin dosage adjustment is improved after years old. Conclusion lung the infection and heart failure patients, using nitroglycerin micro pump therapy can improve the therapeutic effect, less adverse reaction, is worth promoting.

【作者单位】：杭州市红十字会医院心内科;
【基金】：浙江省自然科学基金项目资助(Y2090160)
【分类号】：R563.1
【正文快照】： 老年肺部感染多是多种病原体引起的肺实质炎症,其中细菌感染居多,由于老年患者体质较弱,多合并基础疾病,很容易引起重症肺部感染。肺部感染合并心功能不全患者采用吸氧、利尿等一般治疗效果不佳,有研究指出,硝酸甘油微泵治疗有较好效果[1]。为分析硝酸甘油微泵治疗老年肺部感

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