中药雾化联合离子导入治疗慢性阻塞性肺疾病急性加重期患者35例临床观察

发布时间：2018-01-16 15:01

本文关键词：中药雾化联合离子导入治疗慢性阻塞性肺疾病急性加重期患者35例临床观察　出处：《中医杂志》2016年08期 　论文类型：期刊论文

【摘要】：目的观察中药雾化联合离子导入治疗慢性阻塞性肺疾病急性加重期的临床疗效。方法将70例慢性阻塞性肺疾病急性加重期患者随机分为治疗组和对照组各35例。对照组给予常规西药抗生素及解痉平喘药治疗,治疗组在对照组基础上加用中药雾化及离子导入,每日1次,每次30 min,两组均治疗14天。观察治疗前后患者咳嗽、咯痰、喘息以及湿Up音症状体征积分,检测肺功能及血清C反应蛋白(CRP)与降钙素原(PCT)水平。记录两组患者治疗期间使用抗生素的平均天数,并判定临床疗效。结果治疗组35例中显效30例,好转3例,无效2例,总有效率为94.28%;对照组35例中显效28例,好转3例,无效4例,总有效率为88.57%,两组临床疗效比较差异无统计学意义(P0.05)。治疗组平均抗生素使用天数明显少于对照组(P0.05)。两组治疗后喘息、咳嗽、咯痰及湿Up音症状体征积分较治疗前显著降低(P0.01);治疗后治疗组咳嗽、咯痰积分较对照组改善明显(P0.05)。治疗后两组组间肺功能比较差异无统计学意义(P0.05)。两组患者治疗后CRP、PCT较本组治疗前显著降低(P0.01),且治疗组较对照组降低更明显(P0.05)。结论中药雾化及离子导入能显著改善患者临床症状,降低炎症指标,减少抗生素的应用。
[Abstract]:Objective to observe the clinical effect of Chinese medicine atomization combined with iontophoresis on acute exacerbation of chronic obstructive pulmonary disease. Methods 70 patients with acute exacerbation of chronic obstructive pulmonary disease were randomly divided into treatment group and control group. The control group was treated with routine western medicine antibiotics and antispasmodic drugs. The treatment group in the control group on the basis of adding Chinese medicine atomization and iontophoresis, once a day, 30 minutes each time, both groups were treated for 14 days. Observe the patients before and after treatment cough, sputum. The scores of symptoms and signs of wheezing and wet up were measured. The pulmonary function and serum levels of C-reactive protein (CRP) and procalcitonin (PCT) were measured. The average days of antibiotic use during treatment were recorded. Results in the treatment group, there were 30 cases of remarkable effect, 3 cases of improvement and 2 cases of ineffective. The total effective rate was 94.2828. In the control group, there were 28 cases with remarkable effect, 3 cases with improvement and 4 cases with no effect. The total effective rate was 88.57%. There was no significant difference in clinical efficacy between the two groups. The average days of antibiotic use in the treatment group was significantly less than that in the control group (P 0.05). After treatment, the two groups were wheezing and coughing. The score of symptoms and signs of phlegm and wet up was significantly lower than that before treatment (P 0.01). After treatment, the scores of cough and sputum in the treatment group were significantly improved than those in the control group (P 0.05). There was no significant difference in pulmonary function between the two groups after treatment. CRP was found in the two groups after treatment. PCT was significantly lower than that before treatment, and that of the treatment group was significantly lower than that of the control group. Conclusion Chinese medicine atomization and iontophoresis can significantly improve the clinical symptoms of the patients. Reduce the inflammation index, reduce the use of antibiotics.
【作者单位】：淮北市中医院;安徽中医药大学第一附属医院;
【基金】：国家中医药管理局中医药防治重大疑难疾病临床服务能力建设项目(2014mzfyjs006) 安徽省省级中医发展专项(2014ZY69)
【分类号】：R563.9
【正文快照】： 慢性阻塞性肺疾病(简称慢阻肺)急性加重是指患者症状出现超越日常状态的持续恶化,患者短期内出现咳嗽、咯痰、气促和(或)喘息等症状加重,痰量较前增多,可伴肺功能减退及炎症因子C反应蛋白(CRP)与降钙素原(PCT)升高的表现[1]。中药离子导入治疗是物理治疗方法之一,是结合中药穴

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