长效型吸入剂药物治疗慢性阻塞性肺疾病的临床成效分析

发布时间：2018-01-22 00:13

本文关键词： 慢性阻塞性肺疾病疾病严重程度肺活量长效型吸入剂医疗利用　出处：《泰山医学院》2014年硕士论文　论文类型：学位论文

【摘要】：目的慢性阻塞性肺疾病为重要的呼吸系统疾病,由于其发病率高、死亡率高、医疗耗费高等特点,现已成为一个重要的公共卫生问题。长效型吸入剂为目前COPD的主流治疗。本研究旨在评估长效型吸入剂在慢性阻塞性肺疾病中的治疗效果,从而为优化慢性阻塞性肺疾病患者的的治疗策略提供资料。方法收集2012年09月至2013年08月的慢性阻塞性肺疾病门诊病人(排除哮喘患者和死亡病人)作为研究对象,比较接受长效型吸入剂治疗者与口服药物治疗者疾病严重程度(轻度、中度、重度、极重度)、肺活量(FEV1,用力呼气一秒量)的差异,以及对医疗利用(累积住院日数、急诊次数、急性发作)的影响。对医疗利用累积住院日数、急诊次数、急性发作的影响。数据统计部分采用SPSS 12.0版软件,以描述性、推论性分析及强迫进入复回归分析预测变项进行分析。结果研究结果显示,使用吸入剂病人中在用药前后肺功能的差异优于使用口服药病人。在使用口服药控制COPD的个案中,其疾病严重程度为极重度个案中会影响累积住院日数情况;故,其功能较差者日常生活活动受限,其住院天数就愈多。长效型吸入剂,对于COPD的控制、治疗而对住院天数、急诊次数使用次数、急性发作次数正面意义。结论使用长效型吸入剂病人,可以提高肺功能指标,对于COPD疾病的控制是有利的,并可以有效提高病人生活质量。有效的疾病管理会降低COPD病人再住院率,并提升医疗质量,以获得更大临床效果。
[Abstract]:Objective chronic obstructive pulmonary disease is an important respiratory disease, because of its high incidence, high mortality, high medical costs and other characteristics. It has become an important public health problem. Long-acting inhalants are the mainstream treatment of COPD. This study was designed to evaluate the efficacy of long-acting inhalants in chronic obstructive pulmonary disease (COPD). Methods from September 2012 to August 2013, patients with chronic obstructive pulmonary disease (COPD) from September 2012 to August 2013 were collected. Exclude asthmatic patients and dead patients) as subjects of the study. The severity of disease (mild, moderate, severe, very severe, vital capacity, FEV1, 1 second forced expiratory volume) was compared between the patients treated with long-acting inhalants and those treated with oral medication. And the effect on medical utilization (cumulative hospitalization days, emergency times, acute seizures). The effect of acute attack. The data were analyzed by SPSS 12.0 software to predict variables by descriptive, inferential and forced multiple regression analysis. The difference of lung function between patients with inhalant and before and after administration was better than that with oral administration. The severity of the disease is extremely severe, which will affect the cumulative number of hospital days; Therefore, its function poor people's daily life activity is limited, its hospitalization days are more. The long-acting inhaler, for COPD control, treatment and hospitalization days, emergency use times. Conclusion the use of long-term inhalant can improve the pulmonary function index and is beneficial to the control of COPD disease. Effective disease management can reduce the rehospitalization rate of COPD patients and improve the quality of medical treatment so as to obtain greater clinical effect.
【学位授予单位】：泰山医学院
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R563.9

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