301例支气管扩张症患者的临床分析

发布时间：2018-02-11 09:18

  本文关键词： 支气管扩张症 病因 肺功能 高分辨率计算机断层扫描　出处：《郑州大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的分析支气管扩张症(bronchiectasis,BE)患者的临床特点、胸部高分辨率计算机横断面扫描(high-resolution computed tomograpy,HRCT)及肺功能结果,以增进对BE的认识。方法收集于2015.06.01-2016.06.01收住郑州大学第一附属医院的HRCT确诊的BE患者301例,回顾性分析其年龄、性别、起病年龄、病因、临床症状、胸部HRCT、肺功能及其他资料。结果1.该病在女性的发病率(62.79%)高于男性(37.21%),而且其起病年龄(33.93±19.86)较男性(40.43±20.55)小,差异具有显著统计学意义(P0.01)。2.该病最常见的临床症状依次是咳嗽(84.05%)、咳痰(80.07%)、胸闷(52.6%)、咯血(42.19%)、发热(32.56%)、胸痛(9.3%)及其他。3.特发性是BE最常见病因(62.12%),其次为结核后(19.93%)。4.左肺下叶为最常见病变部位(77.41%),累及全部肺叶的病例最多(25.91%)。5.囊状BE患者最易出现典型的临床表现,即咳嗽、咳痰、胸闷、咯血。6.该研究中108例患者行肺功能检查,69.44%出现阻塞性通气功能障碍;75例阻塞性通气功能障碍的患者FEV1/FVC与HRCT评分呈负相关。结论1.该病在女性的发病率高于男性。2.特发性是BE最常见病因,其次为结核后。3.囊状BE患者的临床表现最明显,更易出现全肺叶受累。4.大部分BE患者出现阻塞性通气功能障碍,其FEV1/FVC与HRCT评分呈现负相关。
[Abstract]:Objective to analyze the clinical characteristics of bronchiectasis patients, the results of high-resolution computed tomograpy HRCTs and pulmonary function in patients with bronchiectasis. Methods 301 patients with be diagnosed in the first affiliated Hospital of Zhengzhou University were collected from January to January 2015.06.01-2016.06.Methods the age, sex, onset age, etiology and clinical symptoms of be were retrospectively analyzed. Results 1. The incidence of HRCTs in women was higher than that in males (62.79) and the onset age was 33.93 卤19.86), which was lower than that in males (40.43 卤20.55). The most common clinical symptoms of the disease were cough 84.05, phlegm 80.07, chest tightness 52.66, hemoptysis 42.1910, fever 32.56r, chest pain 9.30.The most common etiology of be was 62.1212. The most common lesions were 77.41%, and the most common cases involving all the lobes were 25.91%. The patients with cystic be were most likely to have typical clinical manifestations. Cough, expectoration, chest tightness, Hemoptysis. 69.44% of the 108 patients with obstructive ventilation dysfunction and 75 patients with obstructive ventilation dysfunction showed negative correlation with HRCT score. Conclusion 1.The incidence of this disease in women is higher than that in men. 2. Idiopathic is the most common cause of be, The clinical manifestations of patients with cystic be were the most obvious, and the whole pulmonary lobe involvement was more likely. The majority of be patients had obstructive ventilation dysfunction, and their FEV1/FVC was negatively correlated with HRCT score.
【学位授予单位】：郑州大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R562.22
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