颅脑术后患者肺部感染的危险因素及干预效果研究

发布时间：2018-02-20 20:13

  本文关键词： 颅脑手术 肺部感染 危险因素 目标监测 干预措施　出处：《中华医院感染学杂志》2017年01期 　论文类型：期刊论文

【摘要】：目的分析颅脑术后肺部感染的危险因素,探讨其干预效果,为临床诊治提供参考依据。方法选择2013年1月-2014年12月125例开颅手术患者为对照组,另选2015年1-12月64例开颅手术患者为观察组,针对高危因素进行目标监测和干预,采用χ2检验比较两组术后并发肺部感染、限制级抗菌药物的使用、住院时间、病死率的情况。结果单因素分析显示,年龄≥65岁、GCS评分≤7分、预防性应用抗菌药、有吸烟史、ASA评级Ⅱ级、白蛋白水平30g/L、手术时间≥3h、术前血糖8mmol/L、伴有意识障碍、合并基础疾病、呼吸机辅助通气是术后肺部感染的影响因素(P0.05);多因素logistic回归分析显示,GCS评分≤7分、预防性应用抗菌药、有吸烟史、白蛋白水平30g/L、术前血糖8mmol/L、伴有意识障碍、呼吸机辅助通气为术后肺部感染的独立危险因素(P0.05);干预后术后肺部感染率为23.44%,使用特殊级抗菌药6例,平均住院时间(12.00±4.28)d,病死率为7.81%,均较对照组减少(P0.05)。结论颅脑术后肺部感染发生的相关危险因素较多,临床根据这些危险因素采取目标监测和干预,能降低术后肺部感染率及病死率,减少特殊级抗菌药的使用,缩短住院时间,是预防颅脑术后肺部感染的有效措施之一。
[Abstract]:Objective to analyze the risk factors of pulmonary infection after craniocerebral surgery, to explore the effect of intervention, and to provide reference for clinical diagnosis and treatment. Methods 125 patients undergoing craniotomy from January 2013 to December 2014 were selected as control group. In addition, 64 patients undergoing craniotomy from January to December of 2015 were selected as observation group. The objective monitoring and intervention were carried out for high risk factors. 蠂 2 test was used to compare the postoperative pulmonary infection, the use of restricted antibiotics, and the length of stay in hospital between the two groups. Results univariate analysis showed that age 鈮，

本文编号：1519930