尘肺病患者医院感染危险因素分析

发布时间：2018-02-21 15:11

本文关键词： 尘肺医院感染危险因素　出处：《第三军医大学学报》2014年18期 　论文类型：期刊论文

【摘要】：目的探讨尘肺病住院患者发生医院感染的状况并分析其危险因素。方法对本科2006年1月至2013年12月确诊为尘肺病的138例住院患者病例资料进行回顾性分析。结果 138例尘肺病患者中39例发生了医院感染,医院感染发生率为28.26%;检出病原菌16株,检出率为37.21%。单因素分析结果显示,感染组尘肺分期、住院时间、吸烟、血清白蛋白、抗生素使用时间与非感染组比较,差异有统计学意义(P0.05,P0.01)。多因素分析结果显示,尘肺分期(OR=0.019,P=0.004,95%CI:0.001~0.278)、住院时间(OR=1.085,P=0.001,95%CI:1.035~1.137)、抗生素使用时间(OR=1.112,P=0.024,95%CI:1.014~1.220)是其主要危险因素,而血清白蛋白(OR=0.841,P=0.012,95%CI:0.734~0.963)是其保护因素。结论尘肺病住院患者医院感染发生率较高,尘肺分期越严重、住院时间越长、使用抗生素时间越长、血清白蛋白越低,医院感染风险越大。
[Abstract]:Objective to investigate the status of nosocomial infection in patients with pneumoconiosis and to analyze its risk factors. Methods the data of 138 inpatients with pneumoconiosis from January 2006 to December 2013 were retrospectively analyzed. Of 138 patients with pneumoconiosis, 39 had nosocomial infections. The incidence of nosocomial infection was 28.26, 16 strains of pathogenic bacteria were detected, the detection rate was 37.21. The results of univariate analysis showed that the pneumoconiosis stage, hospitalization time, smoking, serum albumin, antibiotic use time of infection group were compared with those of non-infection group. The results of multivariate analysis showed that the main risk factors were the stage of pneumoconiosis (OR 0.019), the percent of CI: 0.001 / 95, the length of stay, the duration of hospitalization, the duration of antibiotic use, and the duration of antibiotic use, OR1.112P0.02495CIW 1.014 / 1.220). Conclusion the incidence of nosocomial infection in patients with pneumoconiosis is higher, the stage of pneumoconiosis is more serious, the longer the length of hospitalization, the longer the use of antibiotics, the lower the serum albumin, the greater the risk of nosocomial infection.
【作者单位】：深圳市职业病防治院职业病科;
【基金】：国家职业病临床重点专科建设项目(WY2011873) 深圳市重大职业病诊疗技术实验室建设项目(CXB201111250112A)~~
【分类号】：R135.2

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