重庆地区670例呼吸道感染患者呼吸道病原体谱IgM的检测和分析

发布时间：2018-02-25 22:23

本文关键词： 呼吸道感染病原体 IgM抗体间接免疫荧光法　出处：《免疫学杂志》2017年05期 　论文类型：期刊论文

【摘要】：目的了解重庆地区呼吸道感染患者病原体流行及分布情况。方法收集我院自2015年1月至2016年3月期间所有呼吸道感染的住院和门诊患者670例,采用间接免疫荧光法检测患者血清中11种呼吸道病原体的Ig M抗体,根据不同性别、不同年龄和不同季节的病原体抗体阳性率以及合并感染情况进行统计分析。结果 1)670例患者中检出病原体抗体290例(290/670,43.28%),其中乙型流感病毒阳性率最高,其他依次为:嗜肺军团菌、肺炎衣原体、肺炎支原体、甲型流感病毒、呼吸道合胞病毒、副流感病毒、腺病毒、柯萨奇病毒A和埃可病毒;检出的病原体抗体阳性290例中,单项感染的224例(224/290,77.24%),双重感染的51例(51/290,17.59%),三重及以上感染15例(15/290,5.17%)。2)所有患者中女性病原体抗体阳性率高于男性(P0.05);不同年龄组呼吸道病原体感染阳性率有明显差异(P0.05)。3)不同季节病原体抗体的阳性率有差异,春冬季的病原体抗体阳性率显著高于夏秋季(P0.05)。结论该地区呼吸道感染患者检出的呼吸道病原体抗体以乙型流感病毒和嗜肺军团菌为主,感染类型以单项病原体感染为主,且可根据不同的流行病学差异进行有效的病原体预防和控制,尤其对在易感人群中注射疫苗有重要意义。
[Abstract]:Objective to investigate the prevalence and distribution of pathogens in patients with respiratory tract infection in Chongqing. Methods 670 inpatients and outpatients with respiratory tract infection were collected from January 2015 to March 2016 in our hospital. Indirect immunofluorescence assay was used to detect IgG antibody of 11 respiratory pathogens in patients' serum. The positive rate of pathogen antibody and co-infection were statistically analyzed in different ages and seasons. Results 290 cases (290 / 670 / 43.28g) of pathogen antibody were detected in 670 patients, among which the positive rate of influenza B virus was the highest, and the other was Legionella pneumophila, the other positive rate was: Legionella pneumophila, the positive rate of influenza B virus was the highest, and the positive rate of influenza B virus was the highest. Chlamydia pneumoniae, Mycoplasma pneumoniae, influenza A virus, respiratory syncytial virus, parainfluenza virus, adenovirus, coxsackie virus A and Echo virus. 224 cases of single infection, 51 cases of double infection, 51 cases of 51 cases of double infection, 15 cases of triple infection and above, 15 cases of triple infection and above.) the positive rate of female pathogen antibody in all patients was higher than that of male group (P 0.05%); the positive rate of respiratory tract pathogen infection in different age groups had significant difference (P 0.05%. 3) there was significant difference in the positive rate of respiratory tract pathogen infection among different age groups. The positive rate of seasonal pathogens antibody was different. The positive rate of pathogen antibody in spring and winter was significantly higher than that in summer and autumn (P 0.05). Conclusion in this area, influenza B virus and Legionella pneumophila are the main pathogens in respiratory tract infection, and the main type of infection is single pathogen infection. It can be used to prevent and control pathogens according to different epidemiological differences, especially to vaccinate susceptible population.
【作者单位】：第三军医大学大坪医院野战外科研究所检验科;
【分类号】：R446.6;R56

【相似文献】