醒脑静联合单元康复法对急性脑卒中偏瘫伴呼吸道感染患者的临床疗效研究

发布时间：2018-02-26 05:27

本文关键词： 醒脑静单元康复急性脑卒中偏瘫呼吸道感染日常生活能力　出处：《中华医院感染学杂志》2017年22期 　论文类型：期刊论文

【摘要】：目的探讨醒脑静联合单元康复法对急性脑卒中偏瘫伴呼吸道感染患者的临床疗效。方法选取2016年3月-12月收治的急性脑卒中偏瘫伴呼吸道感染患者82例,随机分为2组,均采用卒中单元康复,对照组41例采用左氧氟沙星治疗,在此基础上研究组41例采用醒脑静治疗,持续2周,比较两组患者治疗前、治疗1周、治疗2周时炎症因子(TNF-α、IL-2、IL-6)、T淋巴细胞亚群(CD_4~+、CD_8~+、CD_4~+/CD_8~+比值)等,2周后评定生活质量量表,比较临床疗效及不良反应。结果与治疗前比,两组治疗1周、2周时TNF-α、IL-2、IL-6降低,CD_4~+、CD_8~+升高(P0.05);与对照组比,研究组治疗1周、2周时TNF-α、IL-2、IL-6较低,CD_4~+、CD_8~+较高(P0.05);对照组在神经功能、心理职能、社会功能、生活功能上低于研究组,(P0.05);对照组治疗总有效率为70.73%低于研究组的90.24%(P0.05)。结论醒脑静与单元康复对急性脑卒中偏瘫伴呼吸道感染的疗效显著,利于提高日常生活能力,降低炎症和提高免疫功能,安全性高,值得广泛推广。
[Abstract]:Objective to investigate the clinical effect of Xingnaojing combined with unit rehabilitation in patients with acute stroke hemiplegia with respiratory tract infection. Methods 82 patients with acute stroke hemiplegia complicated with respiratory tract infection from March 2016 to December were randomly divided into two groups. All patients were treated with stroke unit rehabilitation, the control group (41 cases) were treated with levofloxacin, and the study group (41 cases) were treated with Xingnaojing for 2 weeks. After 2 weeks of treatment, the inflammatory factor TNF- 伪 and IL-2IL-6 / T lymphocyte subsets CD4 / CD8 / CD8 / CD8 / T were used to evaluate the quality of life scale (QOL), and to compare the clinical efficacy and adverse reactions. The results were compared with those before treatment. Compared with the control group, the TNF- 伪 IL-2IL-2IL-6 decreased CD4- 伪 IL-2IL-6 level at 1 week and 2 weeks after treatment, and the control group had lower CD4- 伪 IL-2IL-6 level than the control group, and the control group had lower CD4- 伪 IL-2IL-6 level, and the control group had a higher level of CD4- 伪 IL-2IL-6 than that of the control group, and the control group had neurologic function, psychological function and social function, while the control group had a lower level of CD4- 伪 IL-2IL-2IL-6 than that of the control group (P < 0.05). The total effective rate of treatment in the control group was 70.73% lower than that in the study group (90.24%). Conclusion Xingnaojing and unit rehabilitation are effective in treating acute stroke hemiplegia with respiratory tract infection, which is beneficial to the improvement of daily living ability. Reduce inflammation and improve immune function, high safety, worthy of extensive promotion.
【作者单位】：海南省人民医院神经外科;
【基金】：海南自然科学基金面上项目(817316)
【分类号】：R56;R743.3

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