新疆部分地区肺结核患者乙肝分布特征及与肝损的关系

发布时间：2018-03-07 19:17

本文选题：肺结核　切入点：乙型病毒性肝炎　出处：《现代预防医学》2014年20期 　论文类型：期刊论文

【摘要】：目的了解肺结核患者乙肝在新疆部分地区的分布特征,并对乙肝的感染情况与肝损的关联性进行分析,为今后肺结核患者感染乙肝情况的预防、控制以及健康教育提供参考。方法采用酶联免疫法(Enzyme-Linked Immuno SorbentAssay,ELISA)检测乙肝的5项血清学指标,并对结果进行描述性流行病学分析。结果肺结核患者HBV感染率、大三阳、小三阳、HBsAg阳性率分别为22.98%、4.80%、0.12%、0.53%。其中受检者血清HBsAg阳性检出率在地区、民族中差异有统计学意义;HBV感染率在地区、民族、年龄中差异有统计学意义。合并大三阳的轻度肺结核患者更易发生肝损。结论乙肝感染情况与性别无关,与地区、民族、年龄有关;在肺结核病人群中开展乙型病毒性肝炎知识宣传教育以及预防工作时要以中老年为重点。同时患有乙肝会使肝损害的可能性增大,在抗结核药物治疗中应积极进行护肝治疗,避免对肝脏的进一步损害。
[Abstract]:Objective to investigate the distribution of hepatitis B in some areas of Xinjiang, and to analyze the relationship between hepatitis B infection and liver damage in order to prevent tuberculosis patients from infecting hepatitis B in the future. Methods five serological indexes of hepatitis B were detected by enzyme linked Immuno assay (Elisa), and the results were analyzed by descriptive epidemiology. The positive rate of HBsAg was 22.98 and 0.120.53, respectively. The positive rate of serum HBsAg in the subjects was in the region, and the difference among the ethnic groups was statistically significant. The difference in age was statistically significant. Mild pulmonary tuberculosis patients combined with San Yang were more likely to have liver damage. Conclusion Hepatitis B infection is not related to sex, but to area, nationality and age. It is necessary to focus on the middle and old age in the propaganda and education of hepatitis B knowledge and prevention among the people with pulmonary tuberculosis. At the same time, the possibility of liver damage will be increased with hepatitis B. Therefore, it is necessary to take active treatment of protecting the liver in the treatment of anti-tuberculosis drugs. Avoid further liver damage.
【作者单位】：新疆医科大学公共卫生学院;
【基金】：国家自然科学基金资助项目(30960328)
【分类号】：R512.62;R521

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