纤维支气管镜灌洗治疗重型颅脑损伤患者肺部感染的临床分析

发布时间：2018-03-08 05:15

本文选题：纤维支气管镜肺灌洗术　切入点：重度颅脑损伤　出处：《中华医院感染学杂志》2015年18期 　论文类型：期刊论文

【摘要】：目的探讨纤维支气管镜肺灌洗术治疗重度颅脑损伤患者肺部感染的临床疗效,为临床降低肺部感染的发生率提供参考。方法选取2011年9月-2014年11月医院接诊的66例重度颅脑损伤发生肺部感染患者,按照入院时间先后顺序将其分为两组,各33例,对照组给予常规治疗,观察组在常规治疗的基础上给予纤维支气管镜肺灌洗术治疗,比较两组患者的治疗情况、各项治疗指标、疗效以及不良反应。结果观察组机械通气时间、发热时间、肺部Up音消失时间、抗菌药物使用时间均短于对照组,观察组感染控制时间、二氧化碳分压优于对照组;观察组细菌培养阳性率、血氧饱和度均高于对照组;观察组的病死率为0.09%、总有效率为90.90%,对照组分别为30.30%、54.45%,两组比较差异均有统计学意义(P0.05);两组不良反应比较差异无统计学意义。结论纤维支气管镜肺灌洗术治疗重度颅脑损伤合并肺部感染的临床疗效良好、安全性较高,值得临床推广应用。
[Abstract]:Objective to investigate the clinical effect of bronchofiberscope lung lavage in the treatment of lung infection in patients with severe craniocerebral injury. Methods 66 patients with severe craniocerebral injury who were hospitalized from September 2011 to November 2014 were divided into two groups according to the order of admission time, 33 cases in each group. The control group was treated with routine therapy, the observation group was treated with bronchofiberscope lung lavage on the basis of routine treatment, and the two groups were compared with each other in terms of treatment condition, treatment index, curative effect and adverse reaction. Results the mechanical ventilation time of the observation group was compared with that of the control group. The infection control time and partial pressure of carbon dioxide in the observation group were better than those in the control group, the positive rate of bacteria culture and blood oxygen saturation were higher in the observation group than in the control group. The fatality rate of observation group was 0.09, the total effective rate was 90.90 and the control group was 30.30 and 54.45.The difference between the two groups was statistically significant (P 0.05), and there was no significant difference in adverse reactions between the two groups. Conclusion the treatment of severe cranium by fiberoptic bronchoscope lung lavage is of no significance. The clinical effect of brain injury complicated with pulmonary infection is good. It is worth popularizing and applying in clinic because of its high safety.
【作者单位】：滨州医学院附属医院重症医学科;
【基金】：山东省科技厅基金资助项目(Z-2014-1-3-46-1)
【分类号】：R651.15;R563.1

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