急性下呼吸道感染对老年稳定性冠心病患者心血管事件发生的影响

发布时间：2018-03-11 03:37

  本文选题：急性下呼吸道感染　切入点：老年　出处：《中华医院感染学杂志》2017年11期 　论文类型：期刊论文

【摘要】：目的探讨急性下呼吸道感染对老年稳定性冠心病患者心血管事件发生的影响。方法选择医院2012年5月-2016年5月老年稳定性冠心病合并急性下呼吸道感染患者156例为感染组,另选择同期老年稳定性冠心病不合并急性下呼吸道感染患者156例为对照组。收集患者临床资料及3个月内心血管事件的发生情况。结果感染组高血压病、慢性阻塞性肺疾病、慢性肾脏病、贫血的分布率高于对照组,差异有统计学意义(P0.05),感染组左室射血分数低于对照组(P0.05),感染组C-反应蛋白、尿素氮水平高于对照组(P0.05);感染组心血管事件的发生率和全因死亡率均高于对照组(P0.05);心血管事件中,感染组新发心房颤动的发生率高于对照组(P0.05);心血管事件患者慢性阻塞性肺疾病、慢性肾脏病、心率≥125次/分、呼吸≥24次/分的发生率高于非心血管事件患者(P0.05),心血管事件患者左室射血分数低于非心血管事件患者(P0.05),心血管事件患者C-反应蛋白、尿素氮水平高于非心血管事件患者(P0.05);logistic多因素回归分析显示:急性下呼吸道感染、慢性肾脏病、心率≥125次/分、呼吸≥24次/分是稳定性冠心病心血管事件的独立影响因素(P0.05)。结论急性下呼吸道感染增加老年稳定性冠心病心血管事件的发生率及全因死亡率,是老年稳定性冠心病心血管事件的独立影响因素。
[Abstract]:Objective to investigate the effect of acute lower respiratory tract infection on cardiovascular events in elderly patients with stable coronary heart disease. Methods 156 patients with stable coronary heart disease complicated with acute lower respiratory tract infection from May 2012 to May 2016 were selected as infection group. In addition, 156 elderly patients with stable coronary heart disease without acute lower respiratory tract infection were selected as control group. The clinical data of the patients and the occurrence of cardiovascular events within 3 months were collected. Results Hypertension, chronic obstructive pulmonary disease (COPD) were observed in the infected group. The distribution rate of anemia in chronic kidney disease was higher than that in control group (P 0.05). The left ventricular ejection fraction (LVEF) in infected group was lower than that in control group (P 0.05). The level of urea nitrogen was higher than that of the control group (P 0.05), the incidence of cardiovascular events and the death rate of all causes in the infected group were higher than those in the control group (P 0.05). The incidence of new atrial fibrillation in the infection group was higher than that in the control group (P 0.05), chronic obstructive pulmonary disease, chronic kidney disease, heart rate 鈮，

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