2011年弥漫性间质性肺疾病的诊治进展

发布时间：2018-03-15 07:24

本文选题：弥漫性间质性肺疾病　切入点：特发性间质性肺炎/特发性肺间质纤维化　出处：《吉林大学》2012年硕士论文　论文类型：学位论文

【摘要】：弥漫性间质性肺疾病(diffuse interstitial lung disease，DILD)是以肺泡壁为主并包括肺泡周围组织及其相邻支撑结构病变的一组疾病；是以弥漫性肺实质、肺泡炎和间质纤维化为基本病理改变，，以活动后呼吸困难，胸部X线可见双肺弥漫性阴影，限制性通气障碍，弥散功能降低和低氧血症为临床特征的异质性疾病群构成的临床-病理实体的总称；是多种原因引起的急慢性肺部疾病的共同结局；是危害人类健康的重要疾病，其发病率及病死率逐年增高［1］。目前，已知的DILD病因近200种，但确切发病机制尚未完全阐明。DILD对现有治疗方法有较为理想效果的相当有限，大多数DILD治疗相当困难。DILD的发病机制及有效的治疗方案已成为国内外探索研究的热点。本文主要就2011年发表的百余篇中英文文献进行复习、整理，以利于临床工作的参考以及为新的研究开拓思路。
[Abstract]:Diffuse interstitial interstitial lung disease (Dild) is a group of diseases consisting mainly of the alveolar wall, including the surrounding alveolar tissue and its adjacent supporting structures, with diffuse pulmonary parenchyma, alveolitis, and interstitial fibrosis as the basic pathological changes. The general term of clinicopathological entity was found in patients with dyspnea after exercise, diffuse shadow of both lungs, restricted ventilation disorder, decreased diffusion function and hypoxemia. It is the common outcome of acute and chronic pulmonary diseases caused by various causes and an important disease that endangers human health. The morbidity and mortality of these diseases are increasing year by year [1]. At present, there are nearly 200 known causes of DILD. However, the exact pathogenesis has not been fully clarified. DILD has a relatively limited effect on the current treatment. Most of the DILD treatment is very difficult. The pathogenesis and effective treatment of Dild have become the hot spot of domestic and international exploration and research. This article reviews and collates more than 100 articles of Chinese and English published in 2011. In order to facilitate the clinical work of reference and for new research ideas.
【学位授予单位】：吉林大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R563.9

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