应用CAT与mMRC量表初筛COPD患者的可行性研究

发布时间：2018-03-17 17:44

  本文选题：CAT量表　切入点：mMRC量表　出处：《浙江大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:本研究通过比较CAT、mMRC量表评估结果与肺功能检查结果之间的相关性,探讨应用量表初步筛查COPD患者的可行性。方法:选择2015年12月～2016年12月浙江大学医学院附属邵逸夫医院肺功能室的COPD病人188例及对照组185例。采用CAT、mMRC量表对研究对象评分,并与肺功能结果进行统计分析。同时选用SF-36评估表评价纳入对象的生活质量。结果:1.CAT评分、mMRC评分与肺功能指标FEV1%pred、FEV1/FVC均有很好的相关性;2.COPD组CAT各项评分、mMRC评分均高于对照组;3.量表在COPD分级评价中没有意义;4.不同分级COPD患者在咳嗽、咳痰、胸闷、气促、活动受限、外出信心六个项目评分均比对照组高,且分级越高评分越高。GOLDⅠ、GOLDⅡ睡眠评分与对照组差异无意义,GOLDⅢ、GOLDⅣ组睡眠评分比对照组高。GOLDⅠ组精力评分与对照组差异无意义,GOLDⅡ、GOLDⅢ、GOLDⅣ组精力评分比对照组高;5.mMRC量表中GOLDⅡ、GOLDⅢ GOLDⅣ分值均比对照组高,且等级越高mMRC评分越高。GOLD Ⅰ评分与对照组差异无意义;6.CAT量表与mMRC量表之间相关性较好;7.CAT评分对识别COPD有意义,当Cut Off值为8.5时,敏感性和特异性最好,分别为87.23%,78.92%。mMRC评分对识别COPD有意义,当Cut Off值为0.5时,敏感性和特异性最佳,分别为82.45%,63.78%。8.COPD 组 SF-36 量表在 GH、HT、PF、RP、BP、VT、MH、SF 八个项目评分均低于对照组,RE项评分两组差异无意义。结论:CAT量表、mMRC量表与肺功能相关性好,可考虑在不能开展肺功能检查的基层医院对COPD高危人群进行初步筛查,然而量表对判断COPD患者病情严重程度没有意义,不能作为分级诊断的依据。
[Abstract]:Objective: to compare the correlation between the evaluation results of CATmMRC and the results of pulmonary function examination. Methods: from December 2015 to December 2016, 188 COPD patients in the lung function room of run run run Shaw Hospital, Zhejiang University Medical College, and 185 control group were selected. At the same time, the quality of life of the subjects was evaluated by using the SF-36 evaluation form. Results 1. Cat score, mMRC score and the pulmonary function index FEV1 / FEV1 / FVC.2.The CAT scores of the COPD group were higher than those of the COPD group. There was no significance in the evaluation of COPD grading in the control group. (4) the patients with different grades of COPD were coughing. The scores of expectoration, chest tightness, shortness of breath, restricted activities and confidence in going out were higher than those in the control group. The higher the grade, the higher. Gold 鈪，

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