支气管扩张症住院患者肺功能损害的危险因素分析

发布时间：2018-04-02 21:01

  本文选题：支气管扩张症　切入点：CT　出处：《石河子大学》2017年硕士论文

【摘要】：目的:总结支气管扩张症住院患者肺功能受损的临床特点,并分析其肺功能损害的危险因素,以引起临床重视;方法:收集2014年1月到2016年5月新疆自治区人民医院呼吸二科经HRCT诊断的支气管扩张症住院患者94例,包括其临床资料、肺功能检查等并进行CT扩张范围程度评分以及分型等,进行统计学分析。结果:1.支扩患者94例,其中男48例,女46例,年龄为(52.33±14.56)岁;病程为(8.24±10.82)年;咳嗽者80例(85.1%),咳痰者79例(84.0%),咯血者15例(16.9%),呼吸困难者36例(38.3%),发热8例(8.5%),胸痛12例(12.8%),乏力(12.8%);其中吸烟26例(27.6%);BMI为(24.48±4.48)Kg/m2;支扩患者性别无明显差异,主要症状以咳嗽、咳痰为主;2.94例支扩患者中共培养出18株病原菌,其中铜绿假单胞菌4株,鲍曼不动杆菌3株,肺炎克雷伯菌3株等,培养阳性率低,未进行进一步分析;3.不同BMI分组之间FEV1%pred、FEV1/FVC、FVC%pred、RV/TLC、DLCO%pred指标无差异;4.4种类型支气管扩张中柱状最多见,且不同类型的支气管扩张在FEV1%pred、FEV1/FVC、FVC%pred、RV/TLC、DLCO%pred之间有差异且有统计学意义(P0.05);柱状支扩肺功能损害较囊状、混合型轻。5.病程、CT评分以及累及肺叶数在不同程度的肺通气功能障碍之间有差异并有统计学意义(P0.05),在弥散功能正常与异常之间同样有差异;且FEV1%pred、FEV1/FVC、FVC%pred和DLCO与病程、CT评分以及累及肺叶数呈负相关(P0.05);年龄仅与DLCO呈负相关;而BMI、年龄、发病年龄、WBC、ESR在不同程度肺通气功能障碍之间无差异(P0.05);结论:病程越长、累及的肺叶数越多,CT评分越高,肺功能损害越重;而囊状、混合型支扩肺功能损害较柱状支扩重。不同BMI分组对支扩肺功能无影响;
[Abstract]:Objective: to summarize the clinical features of pulmonary function impairment in patients with bronchiectasis and to analyze the risk factors of lung function damage in order to attract clinical attention.Methods: from January 2014 to May 2016, 94 patients with bronchiectasis diagnosed by HRCT in Department of Respiratory of Xinjiang Autonomous region people's Hospital were collected, including clinical data, pulmonary function examination, and CT dilatation range score and classification.Statistical analysis was carried out.The result is 1: 1.There were 94 patients with bronchiectasis, including 48 males and 46 females, aged 52.33 卤14.56 years, and the course of disease was 8.24 卤10.82 years.鍜冲椊鑰，

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