高血压脑出血患者下呼吸道感染原因分析

发布时间：2018-04-06 01:22

本文选题：高血压　切入点：脑出血　出处：《中华医院感染学杂志》2014年12期

【摘要】：目的探讨高血压脑出血患者下呼吸道感染临床特点及相关因素,为临床预防治疗提供依据。方法对2010年2月-2013年1月收治的526例高血压脑出血患者临床资料进行回顾性分析,对医院感染率及病死率、病原菌培养、下呼吸道感染的危险因素进行分析,数据采用SPSS13.0统计软件进行处理,用logistic回归分析法进行多因素分析。结果 526例高血压脑出血患者发生下呼吸道感染79例,感染率为15.02%;死亡21例,病死率26.58%;未发生下呼吸道感染患者447例,死亡35例,病死率7.83%,两组患者病死率比较,差异有统计学意义(χ2=6.834,P0.01);79例下呼吸道感染患者中痰培养阳性45例,阳性率56.96%;采用logistic回归分析显示,下呼吸道感染与病情、住院时间、意识状态、吞咽障碍、吸引术、预防性抗菌药物应用、肾上腺皮质激素、合并糖尿病、出血破入脑室有密切关系。结论高血压脑出血患者下呼吸道感染与多方面因素有关,针对其相关危险因素进行预防,对降低下呼吸道感染具有重要作用。
[Abstract]:Objective to investigate the clinical characteristics and related factors of lower respiratory tract infection in patients with hypertensive cerebral hemorrhage, and provide basis for clinical prevention and treatment. Methods in February 2010 -2013 year in January 526 cases of hypertensive cerebral hemorrhage in patients with clinical data were retrospectively analyzed, the rate and death rate of nosocomial infection, pathogenic bacteria culture, the risk factors of lower respiratory tract infection in the analysis. SPSS13.0 software was used for statistical processing, multivariate analysis was performed using logistic regression analysis. Results there were 79 cases of lower respiratory tract infection in 526 cases of hypertensive cerebral hemorrhage, the infection rate was 15.02%; 21 cases died, the mortality rate was 26.58%; 447 patients had lower respiratory tract infection, 35 cases died, the mortality rate was 7.83%, compared the rate of two patients died, the difference was statistically significant (2=6.834, P0.01); 79 cases of lower respiratory tract infection in patients with sputum culture positive in 45 cases, the positive rate was 56.96% by logistic regression; Analysis shows that the lower respiratory tract infection and illness, hospitalization time, state of consciousness, dysphagia, aspiration, prophylactic application of antibiotics, glucocorticoid, diabetes mellitus, intraventricular hemorrhage are closely related with several factors related to infection of lower respiratory tract of the patients with hypertensive cerebral hemorrhage according to the conclusion, the related risk factors for prevention to reduce, which plays an important role in lower respiratory tract infection.

【作者单位】：浙江中医药大学附属绍兴市中医院心内科;绍兴市人民医院心内科;诸暨市人民医院神经外科;
【基金】：浙江省医药卫生科技计划基金资助项目(2011KYA159)
【分类号】：R563.1

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