时间给药法治疗肺肾气阴两虚型老年COPD稳定期的临床研究

发布时间：2018-04-08 18:36

  本文选题：时间给药法　切入点：COPD稳定期　出处：《云南中医学院》2017年硕士论文

【摘要】：目的:观察时间给药法治疗肺肾气阴两虚型老年COPD稳定期的临床疗效。方法:本研究将60例肺肾气阴两虚型老年COPD稳定期患者按照随机原则分为治疗组与对照组。对照组:常规服用中药汤剂补肺定喘汤,每日1剂,早、中、晚3次分服;治疗组:服用中药汤剂补肺定喘汤,每日1剂,早寅时(北京时间4-5时,地方时间与北京时间有时差需校正),晚酉时(北京时间18-19时)2次分服。两组疗程均为14天。将患者治疗前后的肺功能FEV1、中医证候疗效、CAT积分进行观察分析比较。结果:两组病例在治疗前后中医证候疗效比较,差异有统计学意义(P0.05)。研究结果显示:治疗组在中医证候疗效方面优于对照组。两组病例治疗前后中医证候积分比较、肺功能FEV1、m MRC积分、CAT积分比较,差异均有统计学意义(P0.05),研究结果显示:治疗组在改善以上各方面均优于对照组。结论:治疗组在改善肺功能FEV1、中医证候、咳嗽、咳痰、气短、呼吸困难、乏力等症状、m MRC积分及CAT评分优于对照组。治疗过程中,两组病例的安全性指标治疗前后无显著变化,说明两组用药均安全。因此,治疗肺肾气阴两虚型老年COPD稳定期时间给药法优于常规给药法,且用药安全。
[Abstract]:Objective: to observe the clinical effect of time administration on the stable period of COPD in elderly patients with deficiency of lung and kidney qi and yin.Time difference between local time and Beijing time need to be corrected, late unitary time (18-19 hours Beijing time) 2 times.The course of treatment was 14 days in both groups.The pulmonary function FEV 1 and cat score of TCM syndrome were observed and compared before and after treatment.Results: there was significant difference between the two groups before and after treatment.The results showed that the treatment group was superior to the control group in the curative effect of TCM syndrome.The comparison of TCM syndromes and FEV1m MRC and cat scores before and after treatment in the two groups were statistically significant (P 0.05). The results showed that the treatment group was superior to the control group in improving the above aspects.Conclusion: the treatment group is superior to the control group in improving the pulmonary function FEV1, TCM syndromes, cough, expectoration, shortness of breath, dyspnea, fatigue and other symptoms such as MRC score and CAT score.In the course of treatment, the safety indexes of the two groups were not significantly changed before and after treatment, indicating that both groups were safe.Therefore, the treatment of the elderly patients with deficiency of lung and kidney qi and yin was superior to the routine administration method in the stable period of COPD, and the medication was safe.
【学位授予单位】：云南中医学院
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R563.9

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