理气活血法治疗自发性气胸临床观察

发布时间：2018-04-16 02:10

本文选题：自发性气胸 + 气滞血瘀　；参考：《山东中医药大学》2012年硕士论文

【摘要】：目的：观察应用理气活血法治疗自发性气胸（气滞血瘀型）的临床疗效并探讨其作用机制，判定理气活血药物治疗本病证的有效性、安全性。方法：将符合本研究纳入标准的60例患者按照随机、对照的原则分为试验组32例，对照组28例。试验组在西医治疗基础上加用理气活血中药方剂，即血府逐瘀汤加青皮、佛手，水煎300ml，早晚两次餐后半小时温服，每日1剂；对照组采取单纯西医治疗方法。观察两组患者综合疗效、留置引流管时间、住院时间及复发率，并对各项结果进行统计学分析。结果：在综合疗效、留置引流管时间、住院时间及复发率方面，试验组均优于对照组，并具有统计学意义。结论：理气活血药应用于自发性气胸（气滞血瘀型），可以加快胸膜腔内气体吸收，促进胸膜破裂口愈合，与西医常规治疗方法联合应用，可以提高疗效，缩短住院时间，降低复发率。其机理可能与理气活血药物能够改善微循环及供氧，抗炎，缓解气道阻塞，，防止气体陷闭，促进受损部位增生、修复，保护血管内皮细胞，调节免疫力等作用有关。
[Abstract]:Objective: to observe the clinical effect of regulating qi and activating blood circulation in treating spontaneous pneumothorax (qi stagnation and blood stasis type) and explore its mechanism.Methods: 60 patients who met the criteria were randomly divided into two groups: the experimental group (n = 32) and the control group (n = 28).Experimental group on the basis of western medicine treatment plus Liqi Huoxue prescription, namely Xuefu Zhuyu decoction Qingpi, Buddha's hand, decoction 300ml, in the morning and evening half an hour after the meal, 1 dose per day; the control group was treated with simple western medicine.The comprehensive curative effect, the time of indwelling drainage tube, the time of hospitalization and the recurrence rate of the two groups were observed, and the results were analyzed statistically.Results: the experimental group was superior to the control group in the comprehensive curative effect, the time of indwelling drainage tube, the time of hospitalization and the recurrence rate.Conclusion: the application of qi regulating and promoting blood circulation medicine in spontaneous pneumothorax (Qi stagnation and blood stasis type) can accelerate the gas absorption in pleural cavity, promote the healing of ruptured pleural cavity, and combine with the routine treatment of western medicine, which can improve the curative effect and shorten the hospital stay.Reduce the recurrence rate.The mechanism may be related to the effects of regulating qi and activating blood circulation on improving microcirculation and supplying oxygen, anti-inflammation, relieving airway obstruction, preventing gas trap, promoting the proliferation of damaged parts, repairing, protecting vascular endothelial cells, regulating immunity and so on.
【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R561.4

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