盐酸氨溴索治疗高血压脑出血患者术后肺部感染的临床研究

发布时间：2018-04-19 22:16

本文选题：盐酸氨溴索 + 高血压　；参考：《中华医院感染学杂志》2014年01期

【摘要】：目的探讨盐酸氨溴索用于高血压脑出血患者手术后肺部感染治疗的临床意义,提高临床对高血压脑出血术后肺部感染的防治水平。方法选取高血压脑出血术后发生肺部感染的患者300例,随机分为两组各150例,对照组实施常规治疗,观察组在对照组基础上给予盐酸氨溴索静脉注射,对两组患者治疗效果进行评价,且对患者的临床症状、体征和肺部X线表现进行评分,采用SPSS13.0软件进行统计分析。结果观察组临床显效率和总有效率分别为66.67%和93.33%,对照组分别为42.67%和83.33%,两组比较差异有统计学意义(P0.05);两组患者经过治疗症状、体征以及X线检查评分均较治疗前有所降低,治疗后对照组症状、体征以及X线检查评分分别为(4.68±1.86)、(1.09±0.02)、(1.39±0.17)分,观察组分别为(2.06±1.22)、(0.58±0.05)、(0.72±0.15)分,观察组患者降低更为明显,两组比较差异有统计学意义(P0.05);两组患者均无明显不良反应发生,差异无统计学意义。结论盐酸氨溴索是一种安全、高效治疗高血压脑出血术后肺部感染的药物,可以改善患者的临床预后,有着积极的临床应用价值。
[Abstract]:Objective to explore the clinical significance of ambroxol hydrochloride in the treatment of postoperative pulmonary infection in patients with hypertensive intracerebral hemorrhage (hypertensive intracerebral hemorrhage), and to improve the clinical prevention and treatment of pulmonary infection after hypertensive intracerebral hemorrhage. Methods 300 patients with pulmonary infection after hypertensive intracerebral hemorrhage were randomly divided into two groups: the control group (n = 150) received routine treatment, and the observation group received ambroxol hydrochloride intravenous injection on the basis of the control group. The therapeutic effects of the two groups were evaluated, and the clinical symptoms, signs and lung X-ray manifestations were evaluated. The statistical analysis was carried out with SPSS13.0 software. Results the clinical effective rate and total effective rate were 66.67% and 93.33% in the observation group, 42.67% and 83.33% in the control group, respectively. The difference between the two groups was statistically significant (P 0.05). After treatment, the scores of symptoms, signs and X-ray examination in the control group were 4.68 卤1.86, 1.09 卤0.02 and 1.39 卤0.17, respectively, and in the observation group the scores were 2.06 卤1.22, 0.58 卤0.05 and 0.72 卤0.15, respectively. The decrease of the patients in the observation group was more obvious, and the difference between the two groups was statistically significant (P 0.05). The difference was not statistically significant. Conclusion ambroxol hydrochloride is a safe and effective drug for the treatment of pulmonary infection after hypertensive intracerebral hemorrhage. It can improve the clinical prognosis of patients and has positive clinical application value.
【作者单位】：杭州师范大学附属医院神经外科;杭州市江干区闸弄口街道社区卫生服务中心;杭州市第二人民医院神经外科;
【基金】：浙江省卫生厅基金项目(ZW-2010B1018)
【分类号】：R563.1

【参考文献】