疏风解毒胶囊佐治慢性阻塞性肺疾病急性加重期伴肺部感染的临床观察

发布时间：2018-04-25 23:32

本文选题：疏风解毒胶囊 + 慢性阻塞性肺疾病急性加重期　；参考：《中华中医药杂志》2017年01期

【摘要】：目的:观察疏风解毒胶囊在治疗慢性阻塞性肺疾病急性加重期(AECOPD)伴肺部感染的临床治疗效果。方法:将本院收治的100例伴肺部感染AECOPD患者按照入院时间随机纳入对照组与治疗组,各50例。对照组予头孢曲松抗感染治疗,治疗组同时予以疏风解毒胶囊治疗。两组患者同时按AECOPD处理治疗。观察两组患者治疗期间咳嗽、咳痰、肺部Up音变化变化情况,以及治疗前、治疗第3、10天超敏C反应蛋白(hs-CRP)、降钙素原(PCT)、肺部感染评分(CPIS)变化情况,对临床治疗效果进行评价分析。结果:治疗组患者咳嗽、咳痰、肺部Up音平均消失时间小于对照组(P0.05)。治疗3d、10d后,治疗组hs-CRP、PCT、CPIS指标低于对照组(P0.05),其中,治疗组hs-CRP、PCT基本恢复正常参考值水平;治疗组患者有效率大于对照组(P0.05)。结论:联合疏风解毒胶囊治疗能够加快伴肺部感染的AECOPD患者肺部感染控制,促进患者恢复。
[Abstract]:Objective: to observe the clinical effect of Shufeng jiedu capsule in the treatment of acute exacerbation of chronic obstructive pulmonary disease (COPD) with pulmonary infection. Methods: 100 AECOPD patients with pulmonary infection were randomly divided into control group and treatment group. The control group was treated with ceftriaxone and the treatment group was treated with Shufeng jiedu capsule. Both groups were treated with AECOPD. The changes of cough, expectoration and up sound in lung, and the changes of hypersensitive C-reactive protein (hs-CRP), procalcitonin (PCT) and pulmonary infection score (CPISs) were observed during the treatment of the two groups, and the clinical effect was evaluated and analyzed. Results: the average disappearing time of cough, expectoration and lung up sound in the treatment group was less than that in the control group (P 0.05). After 3 days of treatment, the CPIS index of hs-CRPn PCT in the treatment group was lower than that in the control group (P 0.05), among which, the normal reference value of hs-CRPU PCT was basically restored in the treatment group, and the effective rate of the treatment group was higher than that of the control group (P 0.05). Conclusion: combined treatment with Shufeng jiedu capsule can accelerate the control of pulmonary infection and promote the recovery of AECOPD patients with pulmonary infection.
【作者单位】：滁州市第一人民医院呼吸内科;
【分类号】：R563

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