心力衰竭患者肺部感染后炎性因子的变化研究

发布时间：2018-04-26 07:19

本文选题：心力衰竭 + 肺部感染　；参考：《中华医院感染学杂志》2016年16期

【摘要】：目的研究心力衰竭患者肺部感染后炎性因子的变化,为心力衰竭肺部感染的早期诊断和治疗提供参考依据。方法选取2014年6月-2015年10月医院的52例心力衰竭肺部感染患者为A组,52例心力衰竭患者为B组,52例肺部感染患者为C组,比较3组患者血清炎性因子水平,数据采用SAS 6.0软件进行统计分析。结果 A组的炎性因子白细胞介素-6(IL-6)、转化生长因子-β(TGF-β)、肿瘤坏死因子-α(TNF-α)、降钙素原(PCT)及前列腺素E2(PGE2)血清水平分别为(15.35±1.64)pg/ml、(28.98±2.59)ng/ml、(2.76±0.32)ng/ml、(19.39±2.84)ug/L及(252.52±27.97)pg/ml,其均高于B组及C组,差异有统计学意义(P0.05)。结论心力衰竭患者肺部感染的炎性因子呈现高表达状态,且心功能分级及肺部感染程度均对患者上述指标影响较大。
[Abstract]:Objective to study the changes of inflammatory factors after pulmonary infection in patients with heart failure in order to provide reference for early diagnosis and treatment of pulmonary infection in heart failure. Methods 52 patients with heart failure in October -2015 June 2014 were selected as group A, 52 cases of heart failure were B group, 52 cases of pulmonary infection were C group, and 3 groups were compared. The serum levels of inflammatory factors were statistically analyzed with SAS 6 software. Results the inflammatory factors of A group were interleukin -6 (IL-6), TNF - beta (TGF- beta), tumor necrosis factor - alpha (TNF- alpha), calcitonin (PCT) and prostaglandin E2 (PGE2) blood albumin level (15.35 + 1.64) pg/ml, (28.98 + 2.59) ng/ml, (2.76 + 0.32) ng/. Ml (19.39 + 2.84) ug/L and (252.52 + 27.97) pg/ml were higher than those in group B and C group, and the difference was statistically significant (P0.05). Conclusion the inflammatory factors of lung infection in patients with heart failure were highly expressed, and the classification of heart function and the degree of pulmonary infection had great influence on the above standard.

【作者单位】：郑州人民医院心血管内科二区;
【基金】：河南省科技计划基金资助项目项目(16210231003)
【分类号】：R563.1;R541.6

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