中西医结合治疗支气管扩张症稳定期患者的临床疗效

发布时间：2018-04-30 19:42

本文选题：支气管扩张症 + 氨溴索　；参考：《中国全科医学》2014年33期

【摘要】：目的观察中西医结合治疗支气管扩张症稳定期患者的临床疗效。方法选取2012年6月—2013年6月同济大学附属上海市肺科医院呼吸科、肺内科就诊的支气管扩张症稳定期患者120例,采用随机数字表法分为对照组和治疗组,各60例,对照组给予盐酸氨溴索片治疗,治疗组在盐酸氨溴索片治疗基础上给予三拗片,疗程为3个月。观察两组临床疗效,比较治疗前后两组患者临床症状体征积分(咳嗽、咳痰、咯血、发热、呼吸困难、胸闷胸痛、湿Up音)、圣乔治呼吸问卷(SGRQ)评分。结果治疗后对照组临床控制10例、显效22例、有效17例、无效11例,治疗组临床控制18例、显效29例、有效10例、无效3例,两组临床疗效比较,差异有统计学意义(u=2.950,P=0.003)。治疗前,两组患者咳嗽、咳痰、咯血、发热、呼吸困难、胸闷胸痛、湿Up音临床症状体征积分比较,差异均无统计学意义(P0.05);治疗后,治疗组咳嗽、咳痰、咯血、呼吸困难、胸闷胸痛、湿Up音临床症状体征积分较对照组降低(P0.05),且治疗组SGRQ评分及其中的症状、活动、影响评分较对照组降低(P0.05)。结论三拗片联合盐酸氨溴索能显著改善支气管扩张症稳定期患者的临床症状,提高其生活质量。
[Abstract]:Objective to observe the clinical effect of integrated traditional Chinese and western medicine on patients with bronchiectasis at stable stage. Methods from June 2012 to June 2013, 120 stable bronchiectasis patients in Shanghai Lung Hospital affiliated to Tongji University were randomly divided into control group and treatment group with 60 cases each. The control group was treated with ambroxol hydrochloride tablets and the treatment group was treated with Sanao tablets on the basis of ambroxol hydrochloride tablets for 3 months. To observe the clinical effect of the two groups and to compare the scores of clinical symptoms and signs (cough, expectoration, hemoptysis, fever, dyspnea, chest tightness and chest pain, wet up tone, St George's breathing questionnaire) before and after treatment. Results after treatment, there were 10 cases of clinical control, 22 cases of marked effect, 17 cases of effective, 11 cases of ineffective in control group, 18 cases of clinical control, 29 cases of remarkable effect, 10 cases of effective and 3 cases of ineffective in treatment group. The difference between the two groups was statistically significant. Before treatment, there was no significant difference in the scores of cough, expectoration, hemoptysis, fever, dyspnea, chest tightness and chest pain, wet up sound and clinical symptoms and signs between the two groups (P 0.05), after treatment, the treatment group had cough, expectoration, hemoptysis and dyspnea. The scores of clinical symptoms and signs of chest tightness and chest pain, wet up sound were lower than that of control group (P 0.05), and the SGRQ scores, symptoms and activities in the treatment group were lower than those in the control group (P 0.05). Conclusion Sanao tablets combined with ambroxol hydrochloride can significantly improve the clinical symptoms and quality of life of patients with bronchiectasis at stable stage.
【作者单位】：同济大学附属上海市肺科医院呼吸科;
【分类号】：R562.22

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