下呼吸道感染患者C-反应蛋白的临床价值探讨

发布时间：2018-05-01 05:24

本文选题：C-反应蛋白 + 下呼吸道感染　；参考：《现代预防医学》2014年18期

【摘要】：目的探讨血清C-反应蛋白在下呼吸道感染患者中的临床价值。方法选择61例下呼吸道感染患者,分别在治疗前后予以检测血清C-反应蛋白(CRP),血沉(ESR)及血白细胞(WBC),进行对比分析。结果 CRP敏感度为98.36%,WBC+ESR综合指标判断敏感度为34.43%,两种指标判断经χ2检验差异有统计学意义(χ2=37.03,P0.01),即下呼吸道感染治疗前采用CRP指标判断下呼吸道感染的敏感度高于WBC+ESR综合指标判断。治疗后CRP敏感度为49.18%,WBC+ESR综合指标判断敏感度为0.33%,两种指标判断经χ2检验,差异有统计学意义(χ2=26.04,P0.01),即下呼吸道感染治疗后采用CRP指标判断下呼吸道感染的敏感度仍高于WBC+ESR综合指标判断。结论 CRP水平与结合患者的症状和体征,可以指导下呼吸道感染的治疗。C-反应蛋白对下呼吸道感染患者的判断及疗效较血常规及ESR敏感有效,可作为观察疗效和判断预后的指标,避免抗生素过早停用贻误病情,同样也增加了有效避免抗生素过度使用产生耐药性的方法。可指导抗菌药物的合理使用和管理。
[Abstract]:Objective to investigate the clinical value of serum C-reactive protein in patients with lower respiratory tract infection. Methods 61 patients with lower respiratory tract infection were examined for serum C-reactive protein (CRP), erythrocyte sedimentation rate (ESR) and white blood cell (WBC) before and after treatment. Results the sensitivity of CRP was 98.36 and the sensitivity of ESR was 34.43. The difference between the two indexes was statistically significant (蠂 ~ 2 = 37.03, P 0.01). That is, the sensitivity of CRP index to lower respiratory tract infection was higher than that of WBC before the treatment of lower respiratory tract infection. ESR comprehensive index judgment. After treatment, the sensitivity of CRP was 49.18 and the sensitivity of ESR comprehensive index was 0.33. The two indexes were tested by 蠂 2. The difference was statistically significant (蠂 2, 26.04, P 0.01, that is, the sensitivity of using CRP index to judge lower respiratory tract infection after treatment was still higher than that of WBC ESR comprehensive index. Conclusion the level of CRP and the symptoms and signs of patients with lower respiratory tract infection can be guided by the treatment of lower respiratory tract infection. C- reactive protein is more sensitive than blood routine and ESR in judging and curative effect of patients with lower respiratory tract infection. It can be used as an index to observe the curative effect and judge the prognosis, to avoid the prematurely stopping of antibiotics, and to increase the effective methods to avoid the drug resistance caused by the overuse of antibiotics. It can guide the rational use and management of antimicrobial agents.
【作者单位】：贵州省黔南州人民医院呼吸内科;
【分类号】：R56

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