胸部低剂量CT中肺结节自动测量软件的体模研究

发布时间：2018-05-08 12:30

本文选题：肺结节 + 低剂量　；参考：《中国医学计算机成像杂志》2015年04期

【摘要】：目的:比较不同扫描条件下,肺结节自动测量软件的测量精度。方法:对模拟肺体模和结节进行CT图像扫描。使用肺结节专业图像分析软件,进行结节直径、体积测量。计算结节直径、体积、CT值测量的绝对错误率(APE):APE=100×(V_(测量)-V_(实际))/V_(实际)。使用单向方差分析(one-way ANOVA检验)结合StudentNewman-Keuls多重比较法来比较扫描辐射剂量、结节直径、结节密度对APE的影响。结果:将APE按照扫描辐射剂量的不同进行分组比较,发现APE_(直径)、APE_(体_(体积)、APE_(CT值)三者的P值分别为0.44、0.73、0.28;将APE按照扫描方案的不同进行分组比较,发现APE_(直径)、APE_(体积)、APE_(CT值)三者的P值分别为0.37、0.82、0.93,皆无统计学差异,说明扫描辐射剂量和扫描方案的变化对肺结节测量软件的测量结果无显著影响。研究还发现肺结节的直径越大,APE_(直径)越小。而结节直径的不同对APE_(体积)、APE_(CT值)无明显影响。肺结节的密度越小,APE_(直径)越小。不论结节的直径和密度,测量软件得出的APE_(直径)、APE_(体积)皆高于结节的实际值,但都小于25%。而测量软件得出的APE_(CT值)较大。结论:不同的扫描辐射剂量和扫描方案下,肺结节测量软件的测量结果基本一致,说明胸部低剂量CT的的低剂量扫描条件不会影响肺结节测量软件的准确率。不论结节的直径和密度,软件测量得到的直径和体积结果是可信的。
[Abstract]:Objective: to compare the accuracy of automatic measurement software for pulmonary nodules under different scanning conditions. Methods: computed tomography (CT) images were performed on the phantom and nodule of the simulated lung. The diameter and volume of pulmonary nodules were measured with professional image analysis software. The absolute error rate in calculating the diameter of nodules, the volume of CT values and the absolute error rate of measuring the value of CT value are 100 脳 V / V / V / V / T / V / T. Unidirectional one-way ANOVA test was used to compare the effects of scanning radiation dose, nodule diameter and nodular density on APE. Results: the APE was grouped according to the dose of scanning radiation, and the P value of APE was 0.44 / 0.730.28 respectively, and the APE was compared according to the different scanning schemes. It was found that there was no statistical difference among the three groups (P = 0.37 / 0.82 / 0.93), indicating that the changes of scanning radiation dose and scanning scheme had no significant effect on the measurement results of pulmonary nodules. The study also found that the larger the diameter of pulmonary nodules, the smaller the diameter of APE. However, the difference of nodule diameter had no significant effect on the CT value of APEs. The smaller the density of pulmonary nodules, the smaller APEs (diameters). Regardless of the diameter and density of the nodule, the APES (diameter and volume) obtained by the software are higher than the actual value of the nodule, but are less than 25%. The APE_(CT value obtained by the measurement software is larger. Conclusion: the results of lung nodule measurement software are consistent with each other under different radiation doses and different scanning schemes, which indicates that the low dose scanning condition of low dose CT does not affect the accuracy of lung nodule measurement software. Regardless of the diameter and density of the nodules, the results of the software measurements are reliable.
【作者单位】：上海交通大学医学院附属瑞金医院放射科;
【分类号】：R563;R816.4

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