老年痴呆患者合并肺部感染发生率与危险因素分析

发布时间：2018-05-10 09:13

本文选题：血管性痴呆 + 阿尔茨海默病　；参考：《中华医院感染学杂志》2017年05期

【摘要】：目的探讨老年痴呆患者合并肺部感染的高危因素,为临床预防治疗提供依据。方法选择2014年1月-2015年12月在医院住院的老年痴呆患者126例为研究对象,其中血管性痴呆(VD)患者66例,阿尔茨海默病(AD)患者60例;记录患者的一般资料及临床资料,分析老年痴呆患者合并肺部感染率及危险因素。结果 126例患者中42例发生肺部感染,感染率为33.3%,其中上呼吸道感染10例,下呼吸道感染32例;多因素分析结果显示:糖尿病、进食困难、长期卧床、吸烟史、不合理使用抗菌药物、合并肿瘤、低蛋白血症是血管性痴呆患者合并肺部感染的独立危险因素;糖尿病、吸烟史、不合理使用抗菌药物、病程长、合并肿瘤、低蛋白血症是阿尔茨海默病患者合并肺部感染的独立危险因素。结论老年痴呆患者容易并发肺部感染,不同痴呆患者并发肺部感染的危险因素存在差异,而糖尿病、不合理使用抗菌药物、合并肿瘤及低蛋白血症等是血管性痴呆与阿尔茨海默病共同的独立危险因素。
[Abstract]:Objective to explore the high risk factors of pulmonary infection in senile dementia patients and to provide evidence for clinical prevention and treatment. Methods from January 2014 to December 2015, 126 patients with senile dementia, including 66 patients with vascular dementia and 60 patients with Alzheimer's disease (AD), were enrolled in the study, and the general data and clinical data of the patients were recorded. To analyze the lung infection rate and risk factors in senile dementia patients. Results there were 42 cases of pulmonary infection in 126 cases, the infection rate was 33.3%, including 10 cases of upper respiratory tract infection and 32 cases of lower respiratory tract infection, the results of multivariate analysis showed that: diabetes mellitus, eating difficulty, long-term bed rest, smoking history, Irrational use of antimicrobial agents, tumor and hypoproteinemia are independent risk factors of pulmonary infection in patients with vascular dementia, diabetes mellitus, smoking history, irrational use of antibiotics, long course of disease, complicated with tumor, Hypoproteinemia is an independent risk factor for lung infection in patients with Alzheimer's disease. Conclusion senile dementia patients are prone to complicated with pulmonary infection, and the risk factors of pulmonary infection in different dementia patients are different. However, the use of antimicrobial agents is not reasonable in patients with diabetes mellitus. Tumor and hypoproteinemia are common independent risk factors for vascular dementia and Alzheimer's disease.
【作者单位】：新乡医学院第一附属医院护理部;新乡医学院第一附属医院神经内科四病区;新乡医学院第一附属医院神经内科二病区;新乡医学院第一附属医院神经内科三病区;
【基金】：河南省科技发展计划基金资助项目(0224631262)
【分类号】：R563.1;R749.16

【相似文献】