慢性阻塞性肺病合并多脏器功能损害的现况及临床治疗观察

发布时间：2018-05-16 23:23

本文选题：慢性阻塞性肺病 + 肝功能　；参考：《新疆医科大学》2015年硕士论文

【摘要】：目的：通过相关资料分析研究慢性阻塞性肺病合并多脏器功能损害与患者的年龄、性别、合并症等有无相关性并通过治疗过程中观察实验室指标的变化(肝功能、肾功能、BNP、D-二聚体等)来评价治疗过程中不同治疗方案对实验室指标变化的影响。方法：收集2013年2月至2015年2月就诊于我院呼吸科明确诊断慢性阻塞性肺病并已经合并不同程度的两个脏器器官功能损害患者的相关数据进行统计分析,本次研宄中通过治疗前后患者各项指标的变化相对比,来了解不同治疗方案对各项指标变化的影响。结果：入院患者性别、年龄、族别等无统计学差异。肺心病患者经无创呼吸辅助通气对症治疗后可一定程度上的改善心功能、肾功能,与未给予无创呼吸辅助通气患者之间差别有统计学意义。结论：无创呼吸机辅助通气对症治疗可减轻慢性阻塞性肺病合并多脏器功能损害时的心肾功能(实验室指标表现为BNP、D-二聚体、尿酸明显下降,有统计学意义,P0.05)。
[Abstract]:Objective: to study the correlation between multiple organ dysfunction and age, sex and complications in patients with chronic obstructive pulmonary disease (COPD) and to observe the changes of laboratory indexes (liver function, liver function) in the course of treatment. Renal function BNPD-dimer was used to evaluate the effect of different treatment regimens on the changes of laboratory indexes. Methods: from February 2013 to February 2015, the data of patients with chronic obstructive pulmonary disease (COPD) diagnosed in respiratory department of our hospital who had been complicated with different degrees of organ function damage were collected and analyzed statistically. In this study, the effects of different treatment schemes on the changes of indexes were studied by comparing the changes of patients' indexes before and after treatment. Results: there was no significant difference in sex, age and ethnic group. The patients with cor pulmonale can improve their cardiac function and renal function to a certain extent after the treatment of non-invasive respiratory assisted ventilation, and the difference is statistically significant between the patients without non-invasive respiratory assisted ventilation. Conclusion: the treatment of non-invasive ventilator assisted ventilation can reduce the heart and kidney function in patients with chronic obstructive pulmonary disease complicated with multiple organ function damage (the laboratory index is BNP-D-dimer, uric acid is obviously decreased, there is statistical significance (P0.05).
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R563.9

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