一氧化碳中毒肺部感染患者甲襞微循环及脑血流变化研究

发布时间：2018-05-18 02:36

本文选题：一氧化碳中毒 + 肺部感染　；参考：《中华医院感染学杂志》2015年11期

【摘要】：目的研究及观察一氧化碳中毒并发肺部感染患者甲襞微循环及脑血流状态的变化,为其制定治疗干预措施提供依据。方法选取2009年10月-2013年12月在医院进行治疗的235例一氧化碳中毒患者为研究对象,将235例患者根据是否发生肺部感染分为一氧化碳中毒组(A组)160例和一氧化碳中毒肺部感染组(B组)75例,将两组患者的甲襞微循环及脑血流指标进行检测与比较,对B组中不同感染程度者的检测水平进行统计与比较。结果 B组的管襻积分、襻周状态积分及管襻畸形率、白微栓率分别为(1.29±0.15)分、(1.95±0.24)分及(35.46±3.27)%、(1.98±0.25)%,均高于A组的(0.75±0.10)分、(1.02±0.14)分及(19.33±2.15)%、(1.31±0.14)%,差异有统计学意义(P0.05);B组的大脑中动脉Vs及Vd指标,分别为(0.75±0.05)m/s及(0.27±0.04)m/s,均低于A组的(1.08±0.09)m/s及(0.56±0.06)m/s,而PI及RI指标则高于A组,差异均有统计学意义(P0.05)。结论一氧化碳中毒并发肺部感染患者甲襞微循环及脑血流呈现异常的状态,且微循环受感染严重程度的影响较大,因此应重视对该类患者进行甲襞微循环及脑血流的改善。
[Abstract]:Objective to study and observe the changes of nailfold microcirculation and cerebral blood flow in patients with carbon monoxide poisoning complicated with pulmonary infection. Methods 235 patients with carbon monoxide poisoning who were treated in hospital from October 2009 to December 2013 were selected as subjects. 235 patients were divided into two groups: group A (160 cases) and group B (75 cases). The nailfold microcirculation and cerebral blood flow were measured and compared between the two groups. The detection levels of patients with different infection degrees in group B were compared and statistically analyzed. Results in group B, the scores of loop, loop state and abnormal loop were 1.29 卤0.15, 1.95 卤0.24) and 35.46 卤3.27, 1.98 卤0.25, respectively, which were higher than those in group A (1.02 卤0.14) and 19.33 卤2.15 (1.31 卤0.14), respectively. There were significant differences in Vs and VD of middle cerebral artery in P0.050.0B group. They were 0.75 卤0.05)m/s and 0.27 卤0.04m / s, respectively, which were lower than those in group A (1.08 卤0.09)m/s and 0.56 卤0.06), while Pi and RI were higher than those in group A (P 0.05). Conclusion the nailfold microcirculation and cerebral blood flow are abnormal in patients with carbon monoxide poisoning complicated with pulmonary infection, and the microcirculation is greatly affected by the severity of infection. Therefore, attention should be paid to the improvement of nailfold microcirculation and cerebral blood flow in patients with carbon monoxide poisoning.
【作者单位】：唐山市工人医院急诊内科;唐山市工人医院急救中心;唐山市工人医院体检中心;唐山市工人医院中心采血室;
【基金】：河北省科学技术支撑计划基金资助项目(11276103d-90)
【分类号】：R595.1;R563.1

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