可比特雾化吸入对COPD患者单肺通气手术期间呼吸功能的影响

发布时间：2018-05-19 04:34

本文选题：可比特 + 雾化吸入　；参考：《中国老年学杂志》2014年22期

【摘要】：目的探讨可比特雾化吸入对慢性阻塞性肺通气功能障碍(COPD)患者单肺通气(OLV)手术期间呼吸功能的影响。方法对60例伴COPD的贲门癌手术患者随机分为治疗组和对照组,治疗组术中在麻醉机吸气回路中同时给予可比特雾化吸入。观察患者在插管后5 min(T0)(未单肺通气)、单肺通气后10 min(T1)、30 min(T2)、60 min(T3)和单肺通气消除后10 min(T4)的动脉p H值、动脉血氧分压(Pa O2),动脉二氧化碳分压(Pa CO2)、血氧饱和度(Sp O2)和气道峰压(Pmax),记录手术时间、苏醒时间和拔管时间。结果与T0和T4时比较,T1~T3时两组Pa O2、Sp O2均降低;Pa CO2、Pmax均升高(P0.05)。与治疗组比较,T2~T3时对照组Pa O2、Sp O2降低;Pa CO2、Pmax明显升高(P0.05);与对照组比较,对照组p H值降低,Pmax明显高于治疗组(P0.05);与对照组比较治疗组苏醒时间和拔管时间明显缩短(P0.05)。结论可比特雾化吸入在COPD患者单肺通气手术中应用可以提高患者Pa O2和Sp O2,改善其呼吸功能,术后患者苏醒时间和拔管时间也明显缩短,增加了手术的安全性。
[Abstract]:Objective to investigate the effects of nebulization on respiratory function during single lung ventilation (OLVV) in patients with chronic obstructive pulmonary dysfunction (COPD). Methods 60 patients with cardiac cancer with COPD were randomly divided into treatment group and control group. The arterial pH values were observed 5 min after intubation and 10 min after one-lung ventilation, 10 min after one-lung ventilation, 30 min T _ 2 + 60 min T _ 3 and 10 min T _ 4 after one-lung ventilation. Arterial partial pressure of oxygen (PaO2), arterial partial pressure of carbon dioxide (PCO2), arterial oxygen saturation (SPO _ 2) and peak airway pressure (Pmax) were recorded. The operation time, recovery time and extubation time were recorded. Results compared with those at T _ 0 and T _ 4, Pao _ 2 / Sp _ 2 _ 2 decreased and PCO _ (2) P _ (max) increased at T _ (1) O _ (3) and T _ (1) T _ (3) in both groups. Compared with the treatment group, the Pao _ 2 O _ 2 of the control group decreased P0.05P _ (max), the pH value of the control group was significantly higher than that of the control group, and the recovery time and the extubation time of the treatment group were significantly shorter than that of the control group, and that of the control group was significantly higher than that of the control group, and the recovery time and the extubation time of the treatment group were significantly shorter than that of the control group. Conclusion the application of COB nebulization in one-lung ventilation in COPD patients can improve the respiratory function of patients with Pao _ 2 and Sp _ O _ 2, and shorten the recovery time and extubation time of the patients after operation, and increase the safety of the operation.
【作者单位】：潍坊医学院附属益都中心医院麻醉科;
【分类号】：R563.9

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