酮替芬联合沙美特罗替卡松治疗变应性咳嗽的疗效观察

发布时间：2018-05-22 12:52

本文选题：变应性咳嗽 + 咳嗽症状评分　；参考：《重庆医学》2015年07期

【摘要】：目的观察酮替芬联合沙美特罗替卡松治疗变应性咳嗽的临床疗效。方法 94例变应性咳嗽患者分成两组,观察组48例口服酮替芬1mg,每天2次,同时吸入沙美特罗替卡松50/250μg,每天2次。对照组46例口服复方甲氧那明2片,每天3次,治疗时间6周。结果两组患者治疗后较治疗前咳嗽症状评分显著降低,差异有统计学意义(P0.01)。治疗3周后观察组疗效较对照组显著提高(P0.05),6周后观察组疗效比对照组提高更为显著(P0.01)。两组患者不良反应发生率比较差异有统计学意义(P0.05)。结论酮替芬联合沙美特罗替卡松治疗变应性咳嗽较复方甲氧那明疗效更好,适用范围更广,不良反应更少。
[Abstract]:Objective to observe the clinical effect of ketotifen combined with salmeterol in the treatment of allergic cough. Methods Ninety-four patients with allergic cough were divided into two groups: the observation group (n = 48) received ketotifen 1 mg orally twice a day and inhaled salmeterol 50 / 250 渭 g twice a day. The control group (n = 46) was treated for 6 weeks by taking 2 tablets of compound methoxylamine three times a day. Results after treatment, the cough symptom scores in the two groups were significantly lower than those before treatment, and the difference was statistically significant (P 0.01). After 3 weeks of treatment, the curative effect of the observation group was significantly higher than that of the control group. After 6 weeks of treatment, the curative effect of the observation group was significantly higher than that of the control group. There was a significant difference in the incidence of adverse reactions between the two groups (P 0.05). Conclusion ketotifen combined with salmeterolticasone is more effective than compound methoxifen in the treatment of allergic cough.
【作者单位】：湖北省武汉市第一医院呼吸内科;
【基金】：武汉市卫计委2013科研立项基金资助项目(WX13C01)
【分类号】：R56

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