老年耐多药肺结核患者肺部感染的病原菌分布及感染危险因素分析

发布时间：2018-05-26 09:31

本文选题：耐多药肺结核 + 肺部感染　；参考：《中华医院感染学杂志》2014年24期

【摘要】：目的分析老年耐多药肺结核病患者肺部感染病原菌分布及感染危险因素,指导控制预防老年耐多药肺结核病发生肺部感染的临床治疗,降低感染率。方法选取2009-2013年老年耐多药肺结核患者合并肺部感染230例,分离培养病原菌并进行药敏试验,研究老年耐多药肺结核病患者合并肺部感染的危险因素,采用SPSS13.0进行统计处理。结果共发生肺部感染的患者72例,感染率为31.30%,共分离得77株病原菌,其中革兰阳性菌29株占37.66%,革兰阴性菌40株占51.95%,真菌8株占10.39%;合并肺部感染的危险因素主要包括:患者年龄大、住院时间长、肺结核病程长、合并有其他疾病、进行侵入性操作以及为预防性应用抗菌药物。结论老年耐多药肺结核患者肺部感染的发生率高,临床应采取措施控制老年耐多药肺结核患者肺部感染的发生。
[Abstract]:Objective to analyze the distribution of pathogenic bacteria and the risk factors of pulmonary infection in elderly patients with multidrug resistance pulmonary tuberculosis (MDR-TB), to guide the clinical treatment of preventing pulmonary infection in elderly patients with MDR-TB and to reduce the infection rate. Methods A total of 230 elderly patients with MDR-TB complicated with pulmonary infection from 2009 to 2013 were selected. The pathogenic bacteria were isolated and tested. The risk factors of pulmonary infection in the elderly patients with MDR-TB were studied and analyzed by SPSS13.0. Results there were 72 cases of pulmonary infection, the infection rate was 31.30%. A total of 77 strains of pathogenic bacteria were isolated. Among them, 29 Gram-positive bacteria accounted for 37.66, 40 Gram-negative bacteria accounted for 51.95 and 8 fungi accounted for 10.39.The risk factors for complicated pulmonary infection include: the age of the patients, the length of stay in hospital, the long course of tuberculosis, and other diseases. Invasive operations and prophylactic use of antimicrobial agents. Conclusion the incidence of pulmonary infection in elderly patients with multidrug resistant pulmonary tuberculosis is high. Measures should be taken to control the incidence of pulmonary infection in elderly patients with multidrug resistance pulmonary tuberculosis.
【作者单位】：聊城市传染病医院呼吸内科;
【基金】：山东省统计科研重点基金资助项目(2014-227)
【分类号】：R563.1;R521

【共引文献】