重症肺部感染患者盐酸氨溴索气管镜灌洗对肺功能水平的影响研究

发布时间：2018-05-29 17:16

本文选题：盐酸氨溴索 + 气管镜灌洗　；参考：《中华医院感染学杂志》2015年15期

【摘要】：目的研究盐酸氨溴索联合气管镜灌洗对重症肺部感染患者血氧分压(PaO2)、氧合指数(PaO2/FiO2)及血液氧饱和度(SaO2)等水平的影响,为临床治疗提供参考依据。方法选取2012年10月-2013年10月收治的重症肺部感染行气管切开的患者92例,随机将其分为观察组及对照组,每组46例;对照组患者静脉滴入盐酸氨溴索治疗,观察组在对照组基础上联合纤维支气管镜对支气管肺泡进行灌洗以及吸痰治疗,对比两组患者PaO2、PaO2/FiO2及SaO2等水平变化,数据采用SPSS 13.0软件进行统计分析。结果观察组患者治疗后PaO2、PaO2/FiO2及SaO2等水平显著高于治疗前,及对照组治疗后,差异均有统计学意义(P0.05);观察组患者有效率为93.48%,高于对照组的69.57%,差异有统计学意义(P0.05)。结论盐酸氨溴索联合气管镜可有效改善重症肺部感染患者PaO2、PaO2/FiO2及SaO2等水平,并缩短各项治疗时间,提高临床治疗效果。
[Abstract]:Objective to study the effects of ambroxol hydrochloride combined with tracheoscopy lavage on the levels of PaO2, Pao _ 2 / FiO _ 2 and SAO _ 2 in patients with severe pulmonary infection. Methods from October 2012 to October 2013, 92 patients with severe pulmonary infection undergoing tracheotomy were randomly divided into observation group and control group with 46 cases in each group, while patients in control group were treated with ambroxol hydrochloride. The observation group was treated with bronchoalveolar lavage and sputum aspiration combined with fiberoptic bronchoscopy on the basis of control group. The changes of PaO2 / FiO2 and SaO2 were compared between the two groups. The data were analyzed by SPSS 13.0 software. Results after treatment, the levels of Pao _ 2 / Pao _ 2 / FiO _ 2 and SaO2 in the observation group were significantly higher than those before treatment and in the control group (P 0.05), and the effective rate of the observation group was 93.48%, which was higher than that of the control group (69.57%), and the difference was statistically significant (P 0.05). Conclusion Ambroxol hydrochloride combined with tracheoscopy can effectively improve the levels of PaO2 / FIo2 / FIo2 and SaO2 in patients with severe pulmonary infection, shorten the time of treatment and improve the clinical efficacy.
【作者单位】：河南省人民医院呼吸内科;
【基金】：河南省卫生厅自然科学基金资助项目(2011020164)
【分类号】：R563.1

【参考文献】