血清铁蛋白对军团菌肺炎诊断分析

发布时间：2018-06-03 14:06

本文选题：血清铁蛋白 + 军团菌肺炎　；参考：《中华医院感染学杂志》2014年06期

【摘要】：目的通过比较军团菌肺炎及其他类型肺炎患者血清铁蛋白(serum ferritin,SF)水平和治疗前后变化,研究SF在军团菌肺炎诊断中的意义,为军团菌肺炎的早期治疗提供依据。方法共收集2011年3月-2013年3月肺部感染患者121例临床资料,将25例确诊军团菌肺炎患者为军团菌肺炎组、84例细菌性肺炎患者为其他细菌肺炎组、7例支原体肺炎患者为支原体肺炎组、5例病毒性肺炎患者为病毒性肺炎组,用化学发光法检测各组患者治疗前后SF水平,同时统计各组患者生化指标并进行比较,采用SPSS 12.0软件进行统计分析。结果军团菌肺炎组治疗前SF水平为(1589.3±254.9)ng/ml,其他细菌肺炎组(179.1±10.3)ng/ml和病毒性肺炎组(139.8±15.9)ng/ml的SF水平正常,支原体肺炎组SF水平(256.5±32.1)ng/ml有部分患者呈轻度升高,军团菌肺炎组经治疗后SF水平(161.6±28.6)ng/ml显著下降,与其他组比较差异有统计学意义(P0.01);其他生化指标血沉、C-反应蛋白、血钠、血钾、谷丙转氨酶、二氧化碳结合力均有不同程度异常,但不具特异性。结论 SF显著增高对于军团菌肺炎有一定的诊断价值,尤其SF水平增高5倍时,诊断军团菌肺炎的可能性较大。
[Abstract]:Objective to study the significance of SF in the diagnosis of Legionella pneumoniae by comparing the serum ferritin serum-ferritin (SF) levels and changes before and after treatment in patients with Legionella pneumoniae and other types of pneumonia, and to provide evidence for early treatment of Legionella pneumonia. Methods 121 patients with pulmonary infection from March 2011 to March 2013 were collected. Twenty-five patients with Legionella pneumonia were divided into Legionella pneumonia group (n = 84), other bacterial pneumonia group (n = 7), mycoplasma pneumonia group (n = 5), viral pneumonia group (n = 5). The level of SF was detected by chemiluminescence method before and after treatment, and the biochemical indexes of each group were counted and compared, and the statistical analysis was carried out by SPSS 12.0 software. Results the SF level of Legionella pneumonia group was 1589.3 卤254.9 ng / ml before treatment, the SF level of other bacterial pneumonia group (179.1 卤10.3)ng/ml) and viral pneumonia group (139.8 卤15.9)ng/ml) was normal, and that of mycoplasma pneumonia group was slightly higher than 256.5 卤32.1)ng/ml group. In Legionella pneumonia group, the level of SF decreased significantly (161.6 卤28.6)ng/ml), the difference was statistically significant (P 0.01), and other biochemical indexes, such as C-reactive protein, blood sodium, blood potassium, glutamate-pyruvic transaminase, carbon dioxide binding ability, were all abnormal in varying degrees. But not specific. Conclusion the significant increase of SF has certain diagnostic value for Legionella pneumonia, especially when SF level is 5 times higher, the possibility of diagnosing Legionella pneumonia is greater.
【作者单位】：杭州市中医院呼吸内科;
【基金】：杭州市卫乡科研基金项目(20110833B22)
【分类号】：R563.1

【参考文献】