血小板计数对判断肺结核病情的价值探讨

发布时间：2018-06-05 02:24

本文选题：肺结核 + 血小板　；参考：《中国感染与化疗杂志》2014年04期

【摘要】：目的了解外周血小板计数增高对结核病患者病情的诊治价值。方法选择2012年1—6月住院初治肺结核进展期80例(进展期组)、治疗后好转期43例(好转期组)及同期健康体检者89名(对照组)。采用血常规细胞计数仪检测外周血白细胞、血小板计数,中性粒细胞比值;同日送检血红细胞沉降率(ESR)及C反应蛋白(CRP)。SPSS13.0统计软件处理数据。结果进展期组ESR及CRP分别明显高于好转期组(P=0.006 5,P=0.007 3);进展期组血小板计数高于正常参考值上限者占41.94%,均值亦明显高于好转组及对照者(分别为P=0.001 4,P=0.0000);且血小板计数分别与ESR及CRP呈正相关。而白细胞计数及中性粒细胞比值与对照组比较差异无统计学意义(P0.05)。结论结核病患者外周血血小板计数升高,对判断病情的活动性及治疗效果具有一定参考价值。
[Abstract]:Objective to investigate the value of peripheral platelet count increase in the diagnosis and treatment of tuberculosis. Methods from January to June 2012, 80 inpatients with advanced pulmonary tuberculosis (advanced stage group), 43 patients with improvement period (improvement period group) and 89 healthy persons (control group) were selected from January to June 2012. The peripheral white blood cell count, platelet count, neutrophil ratio, erythrocyte sedimentation rate (ESRR) and C-reactive protein (CRP) were measured by routine cell counter, and the data were processed by the statistical software CRPU. SPSS 13.0 on the same day. Results ESR and CRP in the advanced group were significantly higher than those in the improvement group, respectively, and the platelet count of the advanced group was higher than that of the upper limit of the normal reference value (41.94%), and the mean value was significantly higher than that of the improved group and the control group (P 0.001 4U P 0.0000), and the platelet count score of the advanced group was higher than that of the control group (P < 0.05), and the platelet count score of the advanced group was significantly higher than that of the control group. There was no positive correlation with ESR and CRP. There was no significant difference in leukocyte count and neutrophil ratio between the control group and the control group (P 0.05). Conclusion the increase of platelet count in peripheral blood of patients with tuberculosis has certain reference value in judging the activity of the disease and the therapeutic effect.
【作者单位】：同济大学附属上海市肺科医院结核病诊疗中心;上海市结核病(肺)重点实验室;
【基金】：国家自然科学基金(30872364,81172806)
【分类号】：R521

【相似文献】