计算机辅助胸腔积液的CT测量方法

发布时间：2018-06-13 08:09

本文选题：医学图像 + 三维重构　；参考：《宁波大学》2017年硕士论文

【摘要】：胸腔积液量的多少是临床治疗所不可或缺的重要数据,直接关系到治疗方案的确定以及疗效的判定。胸腔积液一般通过X线检查、B超检查、胸部CT检查均能发现。但是对于具体积液量的判定,却都缺少明确的量化指标,与循证医学理论相驳。本文定量研究的相关工作流程:包括实验素材的获取,对实验体进行CT断层扫描并获取图像数据,应用Marching cube算法对胸部CT图像进行三维重构,过程中辅以图形分割修补模型等相关操作,创建所需的三维模型后测量积液体积。然后对过程中尤为重要的三维重构算法以及积液体积的精准测量作以详细的阐述。实验结果表明,本文运用的Marching cubes算法能够在体素中以三角面片逼近等值面的方法较好地提取出胸腔积液的表面模型,再根据剖分方法计算出积液体积。并通过若干次对实验体素材的定量注水试验,予以论证本方法的准确性。经验证,因受图像精度、实验体素材的完整性影响,验证性实验的理论数据与实际测得存在差异,但是对于积液的定量较之前精度有了明显提升,可为临床治疗提供数据支持。
[Abstract]:The amount of pleural effusion is an indispensable and important data for clinical treatment, which is directly related to the determination of treatment plan and the evaluation of curative effect. Pleural effusion can be found by X-ray examination, B-ultrasound examination and chest CT examination. However, there is a lack of clear quantitative indicators for the determination of the specific amount of fluid accumulation, which contradicts the theory of Evidence-Based Medicine (Evidence-based Medicine). The related work flow of quantitative research in this paper includes the acquisition of experimental materials, CT tomography scanning and image data acquisition, and 3D reconstruction of chest CT images by Marching cube algorithm. In the process, the required 3D model is created and the volume of fluid is measured by using the related operations such as the graph segmentation and repair model. Then the three-dimensional reconstruction algorithm and the accurate measurement of liquid volume are described in detail. The experimental results show that the Marching cubes algorithm proposed in this paper can extract the surface model of pleural effusion and calculate the volume of pleural effusion according to the method of triangulation. The accuracy of this method is proved by several quantitative water injection tests. Because of the influence of image precision and the integrity of the experimental material, the theoretical data of the validation experiment are different from the actual measurement, but the quantitative accuracy of the hydrops has been improved obviously, which can provide data support for clinical treatment.
【学位授予单位】：宁波大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R561.3;TP391.41

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