老年患者肺部感染病原菌分布及耐药性分析

发布时间：2018-06-17 05:42

本文选题：肺部感染 + 老年患者　；参考：《中华医院感染学杂志》2017年24期

【摘要】：目的探讨老年患者肺部感染病原菌分布及耐药性,为临床选取抗菌药物预防和治疗肺部感染提供依据。方法选取2016年1月-2016年12月医院收治的220例老年肺部感染患者临床病例资料回顾性分析,对肺部感染患者的病原菌分布及耐药性进行检测分析。结果 220例老年肺部感染患者经痰培养送检率为100%,阳性检测率为62.7%,共培养出病原菌206株,以革兰阴性菌为主,共125株占60.7%;对青霉素G、哌拉西林、左氧氟沙星和红霉素耐药性较高,均65%,金黄色葡萄球菌、肺炎链球菌和表皮葡萄球菌对呋喃妥因耐药率较低,均10%。结论老年肺部感染患者对抗菌药物具有较高的耐药性,及时了解病原菌分布情况及耐药性有助于临床医生选取合理的抗菌药物,从而减少肺部感染发生率及病死率。
[Abstract]:Objective to investigate the distribution and drug resistance of pathogenic bacteria in elderly patients with pulmonary infection, and to provide evidence for clinical selection of antimicrobial agents to prevent and treat pulmonary infection. Methods the clinical data of 220 elderly patients with pulmonary infection from January 2016 to December 2016 were retrospectively analyzed, and the distribution of pathogenic bacteria and drug resistance in patients with pulmonary infection were analyzed. Results the rate of sputum culture was 100 and the positive rate was 62.7% in 220 elderly patients with pulmonary infection. 206 strains of pathogenic bacteria were cultured, 125 strains were mainly Gram-negative bacteria (60.7%), penicillin G, piperacillin, and piperacillin were detected. The drug resistance of levofloxacin and erythromycin was higher, and the resistance rate of Staphylococcus aureus, Streptococcus pneumoniae and Staphylococcus epidermidis to furantoin was 10%. Conclusion elderly patients with pulmonary infection have higher antimicrobial resistance. Timely understanding of the distribution of pathogenic bacteria and drug resistance is helpful for clinicians to select reasonable antimicrobial agents so as to reduce the incidence of pulmonary infection and mortality.
【作者单位】：重庆市开州区人民医院感染科;重庆市开州区人民医院肛肠科;
【分类号】：R563.1

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