老年重症肺炎患者病原菌耐药性及死亡相关因素分析

发布时间：2018-06-20 19:46

  本文选题：重症肺炎 + 老年患者　； 参考：《中华医院感染学杂志》2014年17期

【摘要】：目的分析老年重症肺炎患者临床特点、病原菌分布及耐药性特点,探讨老年重症肺炎患者死亡的危险因素。方法回顾性分析2012年9月-2013年6月医院收治的81例重症肺炎患者的临床资料,采用SPSS17.0软件进行统计分析。结果痰液标本中共分离出病原菌110株,其中革兰阴性菌83株占75.5%,革兰阳性菌14株占12.7%,真菌13株占11.8%;革兰阴性菌以铜绿假单胞菌和不动杆菌属最为常见,铜绿假单胞菌对庆大霉素、阿米卡星、亚胺培南/西司他丁敏感率分别为71.0%、80.6%、80.6%,不动杆菌属对头孢他啶及亚胺培南/西司他丁敏感率分别为53.3%、80.0%;年龄≥65岁、累计器官≥3个是老年重症肺炎患者死亡的危险因素(P0.05)。结论对年龄65岁并有多器官功能受损的患者应引起重视并积极综合治疗,对降低重症肺炎病死率具有重要意义。
[Abstract]:Objective to investigate the risk factors of death in elderly patients with severe pneumonia by analyzing their clinical characteristics, distribution of pathogens and drug resistance. Methods the clinical data of 81 patients with severe pneumonia from September 2012 to June 2013 were analyzed retrospectively. SPSS 17.0 software was used to analyze the clinical data. Results A total of 110 strains of pathogenic bacteria were isolated from sputum, of which 83 were Gram-negative bacteria (75.5%), 14 Gram-positive bacteria (12.7m), 13 fungi (11.8B), and Gram-negative bacteria (Pseudomonas aeruginosa) and Acinetobacter (Acinetobacter) were the most common. The sensitivities of Pseudomonas aeruginosa to gentamicin, amikacin, imipenem / cilastatin were 71.0 and 80.6, respectively. The susceptibility rates of Acinetobacter to ceftazidime and imipenem / cilastatin were 53.3% and 80.00.The sensitivity rates of Acinetobacter to ceftazidime and imipenem / cilastatin were 53.3% and 80.0 years, respectively. Accumulative organ 鈮，

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