PEF与ACT监测支气管哮喘相关性探讨

发布时间：2018-06-23 17:41

本文选题：支气管哮喘 + 呼吸峰流速（PEF）　；参考：《大连医科大学》2012年硕士论文

【摘要】：研究目的：探讨哮喘控制测试(asthma control test, ACT)与最大呼气峰流速(PEF)作用的相关性，帮助支气管哮喘患者更佳准确、简便的进行自我监测，，提高患者的依从性。研究方法： 1.研究设计：本研究设计为非双盲、前瞻性、开放、研究。 2.研究对象：选择我院自2011年8月到2012年4月之间门诊收入的确诊为支气管哮喘的患者20例，患者均服用吸入性激素进行缓解期的降阶梯治疗。按照患者门诊时肺功能FEV1%结果把疾病分为轻度、中度和重度哮喘，比较各组ACT差别。 3.监测、记录设备：上海丸博科技有限公司科卡峰速仪(60-850L/min),型号PEF-3；国际哮喘联盟提供哮喘监测日记。 4.研究步骤：对入组患者均进行PEF监测，测定时间是每天2次,为早晨6:30-7:30和晚上18:30-19:30，每次测定3次，取最大值记录于哮喘日记，并如实填写哮喘控制测试。每四周随访1次，了解其PEF及ACT监测情况,。PEFpred%个人预计值80%为哮喘控制,个人预计个值80%为哮喘未控制，哮喘控制测试20分为哮喘未控制;20~25分为哮喘控制。结果：ACT评分20分组与ACT评分20~25分组PEFpred%比较,差异有统计学意义(P0.01)。PEFpred%个人预计值80%组与PEFpred%个人预计值80%组ACT评分比较,差异有统计学意义(P0.01)。ACT评分与PEFpred%具有线性相关关系, P 0.001。PEF评分在轻、中度之间无显著差异（P0.05），PEF评分在中、重度之间无显著差异（P0.01）, PEF评分在轻度与重度之间为P＝0.006，存在显著性差异。结论: ACT积分与支气管哮喘患者的PEF值有较好的相关性，同时PEF监测对于轻、中度的哮喘患者更具有监测意义。
[Abstract]:Objective: to investigate the relationship between asthma control test (asthma control test, ACT) and peak expiratory flow rate (PEF) in order to improve the compliance of asthma patients. Methods: 1. Research design: this research design is non-double blind, prospective, open, research. 2. Participants: twenty patients with bronchial asthma diagnosed from August 2011 to April 2012 were all treated with inhaled sex hormones. The disease was divided into mild, moderate and severe asthma according to the FEV 1% results of outpatient, and the difference of ACT in each group was 3. 3%. Monitoring, recording equipment: Shanghai Maru Technology Co., Ltd. Koka peak speed meter (60-850 L / min), model PEF-3; International Asthma Alliance provides asthma monitoring diary. 4. Steps of the study: PEF was monitored twice a day for 6: 30-7: 30 in the morning and 18: 30-19: 30 in the evening. The maximum value was recorded in the asthma diary and the asthma control test was filled out truthfully. The patients were followed up once every four weeks to find out the PEF and ACT monitoring. The predicted values of PEF and ACT were 80% of asthma control, 80% of individual predictive values were uncontrolled asthma, and 20 of asthma control tests were divided into uncontrolled asthma and uncontrolled asthma. Results compared with ACT score 20 and ACT 20 / 25, the difference was statistically significant (P0.01) .PEFpred% personal predictive value was 80% and PEFpred% was 80%. The difference was statistically significant (P0.01) .ACT score had a linear correlation with PEFpred%, P 0.001. There was no significant difference between mild and moderate PEF scores (P0.05), there was no significant difference between severe and moderate PEF scores (P0.01), PEF scores between mild and severe PEF scores were 0.006, there was significant difference. Conclusion: ACT score has a good correlation with PEF in asthma patients, and PEF monitoring is more significant for mild and moderate asthma patients.
【学位授予单位】：大连医科大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R562.25

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