住院患者肺部感染真菌分布及其耐药性调查

发布时间：2018-06-28 02:46

本文选题：真菌 + 肺部感染　；参考：《中国消毒学杂志》2016年09期

【摘要】：目的了解医院住院患者肺部感染真菌的分布及耐药情况,为临床合理选用抗真菌药物提供科学依据。方法通过临床标本真菌分离培养鉴定和药敏试验方法,对某医院住院肺部感染患者送检病原学标本进行检测与分析。结果从该医院住院肺部感染患者送检的病原学标本中共检出真菌685株,包括白假丝酵母菌539株,占78.69%;近平滑念珠菌86株,占21.31%。白假丝酵母菌感染患者的原发病主要是心肺合并症和慢性肺部感染性疾病;近平滑念珠菌感染患者原发病则主要是医疗相关性肺炎和心肺合并症。临床分离的真菌对伊曲康唑和氟康唑已经产生耐药,但对其他抗真菌药物敏感。结论住院患者肺部感染真菌以白假丝菌酵母菌为主,且对抗真菌药物已经产生耐药现象,应加强真菌感染监测。
[Abstract]:Objective to understand the distribution and drug resistance of the pulmonary infection fungi in hospitalized patients, and to provide scientific basis for the rational selection of antifungal drugs in clinic. Methods the pathogenic samples of the hospitalized pulmonary infection patients in a hospital were detected and analyzed by the method of isolation, culture identification and drug sensitivity test of clinical specimens. The results were from the hospital. 685 strains of fungi, including 539 strains of Candida albicans, 86 strains of Candida albicans, and 86 of Candida albicans infected by Candida 21.31%. were found to be mainly cardiopulmonary complications and chronic pulmonary infection, and the primary disease of patients with Candida albicans was mainly medical treatment. Associated pneumonia and cardiopulmonary complications. The clinically isolated fungi have been resistant to itraconazole and fluconazole, but are sensitive to other antifungal drugs. Conclusions Candida albicans are the main pathogens of pulmonary infection in hospitalized patients, and resistance to fungal drugs has been produced. Fungal infection monitoring should be strengthened.
【作者单位】：贵州医科大学第三附属医院;
【基金】：贵州省黔南州社会发展科技项目(黔南科合社字[2013]20号)
【分类号】：R563.1;R446.5

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