补肺活血胶囊辅助治疗慢性阻塞性肺疾病患者肺部感染的临床研究

发布时间：2018-06-28 16:03

本文选题：补肺活血胶囊 + 慢性阻塞性肺疾病　；参考：《中华医院感染学杂志》2014年05期

【摘要】：目的探讨补肺活血胶囊治疗辅助治疗慢性阻塞性肺疾病(COPD)合并肺部感染的临床可行性,为提高COPD合并肺部感染的临床诊治水平提供参考。方法选取2010年1月-2013年1月收治的COPD合并肺部感染125例患者为研究对象,采用SPSS16.0软件对各变量进行正态性检验和描述性分析,计量资料采用t检验,计数资料比较则采用χ2检验;对所有患者均在抗菌药物的基础上采用补肺活血胶囊治疗,分析其在治疗前后肺功能、血气指标上的改善情况。结果 SaO2和血浆比黏度治疗前后无明显变化(P0.05);治疗前用力肺活量、第1秒钟用力呼吸量、用力肺活量一秒率分别为:(1.984±0.057)L、(3.356±0.124)L、(0.593±0.025)%;治疗后分别为:(2.537±0.099)L、(3.779±1.219)L、(0.813±0.216)%,治疗前后比较差异有统计学意义(P0.05);临床症状体征积分、血气分析、血液流变学以及免疫学治疗前后比较,差异均有统计学意义(P0.05)。结论补肺活血胶囊可提高COPD合并肺部感染的肺功能、血液流变学和临床症状体征,且安全性高。
[Abstract]:Objective to explore the clinical feasibility of Bufei Huoxue capsule in the treatment of chronic obstructive pulmonary disease (COPD) complicated with pulmonary infection, and to provide reference for improving the level of diagnosis and treatment of COPD complicated with pulmonary infection. Methods from January 2010 to January 2013, 125 patients with COPD complicated with pulmonary infection were selected as the study objects. The normal test and descriptive analysis of each variable were performed by SPSS 16.0 software. T test was used to measure the data. All patients were treated with Bufei Huoxue capsule on the basis of antimicrobial agents, and the improvement of lung function and blood gas index before and after treatment were analyzed. Results there was no significant change in SaO2 and plasma specific viscosity before and after treatment (P0.05). The second rate of forced vital capacity was (1.984 卤0.057) L, (3.356 卤0.124) L, (0.593 卤0.025), (2.537 卤0.099) L, (3.779 卤1.219) L, (0.813 卤0.216), respectively. There were significant differences before and after treatment (P0.05), the scores of clinical symptoms and signs, blood gas analysis, hemorheology and immunology before and after treatment were statistically significant (P0.05). Conclusion Bufei Huoxue capsule can improve pulmonary function, hemorheology and clinical symptoms and signs of COPD complicated with pulmonary infection, and has high safety.
【作者单位】：宁夏第五人民医院石嘴山中心医院内三科;石嘴山市惠农区燕子墩中心卫生院;石嘴山市惠农区园艺卫生服务站;
【基金】：石嘴山卫生局一般规划基金项目(NS-2009C类-072)
【分类号】：R563.9

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