痰热清联合抗菌药物治疗老年患者肺部感染的临床疗效分析

发布时间：2018-06-28 20:00

本文选题：老年患者 + 肺部感染　；参考：《中华医院感染学杂志》2016年04期

【摘要】：目的探讨痰热清注射液联合抗菌药物治疗老年患者肺部感染的临床疗效及安全性,为改善老年肺部感染临床疗效、减少患者不良反应提供依据。方法回顾性分析2013年3月-2015年4月医院收治的68例老年肺部感染患者临床资料,将其随机分为观察组和对照组各34例,对照组患者给予单纯抗菌药物治疗,观察组患者给予痰热清注射液联合抗菌药物进行治疗,两组疗程均为两周;观察两组患者治疗期间不良反应发生率及治疗后临床疗效,采用SPSS11.0软件进行统计分析。结果观察组临床治疗显效24例,显效率70.59%,总有效率为91.18%,对照组患者显效16例,显效率47.06%,治疗总有效率为64.71%,两组临床疗效率比较差异有统计学意义(P0.05);观察组患者临床症状控制时间及住院时间均短于对照组,组间比较差异有统计学意义(P0.05);两组患者均有3例发生不良反应,组间比较差异无统计学意义。结论联合使用痰热清注射液和抗菌药物治疗老年肺部感染可有效减少患者临床症状,临床疗效显著,不良反应较少,安全性高。
[Abstract]:Objective to investigate the clinical efficacy and safety of Tanreqing injection combined with antimicrobial agents in the treatment of pulmonary infection in elderly patients, so as to provide evidence for improving the clinical efficacy of pulmonary infection in elderly patients and reducing adverse reactions. Methods the clinical data of 68 elderly patients with pulmonary infection in our hospital from March 2013 to April 2015 were analyzed retrospectively. They were randomly divided into observation group (n = 34) and control group (n = 34). Patients in control group were treated with antimicrobial agents. The patients in the observation group were treated with Tanreqing injection combined with antimicrobial agents for two weeks. The incidence of adverse reactions and the clinical effect after treatment were observed and analyzed by SPSS 11.0 software. Results in the observation group, 24 cases were treated with remarkable effect, the effective rate was 70.599.The total effective rate was 91.18 and 16 cases in the control group. The effective rate was 47.06 and the total effective rate was 64.71. There was significant difference between the two groups (P0.05). The clinical symptom control time and hospitalization time of the observation group were shorter than that of the control group. The difference between the two groups was statistically significant (P0.05); there were 3 cases of adverse reactions in both groups, but there was no significant difference between the two groups. Conclusion combined use of Tanreqing injection and antimicrobial agents in the treatment of senile pulmonary infection can effectively reduce the clinical symptoms, clinical efficacy is significant, less adverse reactions, high safety.
【作者单位】：滨州市人民医院干部保健科;滨州市人民医院药剂科;滨州市人民医院心内科;滨州市人民医院急救站;
【基金】：山东省自然科学基金资助项目(2011MS1102)
【分类号】：R563.1

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