支气管哮喘急性发作期的病原学分析

发布时间：2018-07-12 07:46

本文选题：支气管哮喘 + 急性发作期　；参考：《中华医院感染学杂志》2014年01期

【摘要】：目的分析支气管哮喘急性发作期的病原菌分布特点,为临床合理应用抗菌药物提供参考。方法选择2007年7月-2011年12月医院治疗的136例支气管哮喘急性发作期患者为研究对象,采集患者的痰液、血液进行病原学检测,观察病原体分布特点。结果 136例支气管哮喘急性发作期患者中检出支原体属30株,检出率为22.1%,检出衣原体属33株,检出率为24.3%,两者比较差异无统计学意义;检出合胞病毒19株,检出率为14.0%,明显高于其他病毒的检出率,差异有统计学意义(P0.05);检出卡他莫拉菌36株,检出率为26.5%,与其他细菌的检出率比较,差异有统计学意义(P0.05)。结论支气管哮喘急性发作与病原体感染关系密切,其中病毒感染呼吸道合胞病毒的检出率最高,非典型微生物感染支原体属与衣原体属的检出率差异不大,细菌感染卡他莫拉菌的检出率最高,临床上可根据病原体分布特点进行合理用药。
[Abstract]:Objective to analyze the distribution of pathogenic bacteria in acute attack of bronchial asthma and to provide reference for the rational application of antimicrobial agents in clinic. Methods from July 2007 to December 2011, 136 patients with acute attack of bronchial asthma were selected as study objects. Sputum was collected from patients, blood was detected by etiology, and pathogen distribution was observed. Results 30 strains of Mycoplasma and 33 strains of Chlamydia were detected in 136 patients with acute attack of bronchial asthma. There was no significant difference between them, 19 strains of syncytial virus were detected. The detection rate was 14.0, significantly higher than the detection rate of other viruses, the difference was statistically significant (P0.05); 36 strains of Mora carinii were detected, the detection rate was 26.5, compared with other bacteria, the difference was statistically significant (P0.05). Conclusion there is a close relationship between acute attack of bronchial asthma and pathogen infection. The detection rate of respiratory syncytial virus infected by virus is the highest, while the detection rate of mycoplasma and chlamydia is not different from that of mycoplasma and chlamydia in atypical microorganism. The detection rate of bacterial infection was the highest, which could be used reasonably according to the distribution of pathogens.
【作者单位】：山西医科大学第一医院呼吸科;
【基金】：山西省自然科学基金项目(2012011037-3)
【分类号】：R562.25

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