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哮喘急性发作期患者血清和肽素水平的变化及意义

发布时间:2018-07-15 22:55
【摘要】:目的探讨支气管哮喘急性发作期患者血清和肽素(Copeptin)水平的变化及其临床意义。方法将87例支气管哮喘急性发作期患者根据哮喘严重程度分为轻、中、重度3组,采用ELISA法检测各组血清Copeptin水平,并对血清Copeptin水平与APACHEⅡ评分、血清C反应蛋白(CRP)水平进行相关性分析。结果轻度组、中度组、重度组患者血清Copeptin水平依次升高,各组两两比较差异均有统计学意义(P0.01);血清Copeptin水平与APACHEⅡ评分、血清CRP水平均呈显著正相关(P0.05)。结论血清Copeptin参与了哮喘急性发作患者的机体应激反应,可作为判断哮喘患者病情严重程度及预后的参考指标。
[Abstract]:Objective to investigate the changes and clinical significance of serum and peptide levels in patients with acute attack of bronchial asthma. Methods 87 patients with acute attack of bronchial asthma were divided into 3 groups according to the severity of asthma. The levels of Copeptin in serum were detected by Elisa, and the levels of Copeptin and Apache 鈪,

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