结核感染T细胞斑点试验对艾滋病合并肺结核的临床诊断价值
发布时间：2018-07-18 10:17
【摘要】：目的评价结核感染T细胞斑点试验(T-SPOT.TB)诊断艾滋病合并肺结核的临床应用价值,以利于疾病诊断与鉴别诊断。方法选取45例合并肺结核的艾滋病患者(研究组)及30例未感染肺结核的艾滋病患者(对照组)行T-SPOT.TB检测,并同时行结核菌素纯蛋白衍生物(PPD)试验。结果研究组T-SPOT.TB阳性率为80.0%,显著高于对照组13.3%(χ2=32.14,P0.01),PPD试验在两组间的阳性率分别为13.3%和6.7%;研究组CD4+T细胞计数≥200/μl及200/μl的患者中T-SPOT.TB检测阳性率分别为86.7%和76.7%,差异无统计学意义;T-SPOT.TB检测艾滋病合并肺结核的敏感性为80.0%、特异性为76.7%,阳性似然比6.0,阴性似然比0.1;在PPD试验中分别为13.3%、93.3%、2.0、0.9。结论 T-SPOT.TB对艾滋病合并肺结核具有较高的诊断效能。
[Abstract]:Objective to evaluate the clinical value of T cell spot test (T-SPOT.TB) in the diagnosis of AIDS complicated with pulmonary tuberculosis. Methods T-SPOT.TB was detected in 45 AIDS patients with pulmonary tuberculosis (study group) and 30 AIDS patients without pulmonary tuberculosis (control group), and the PPD test was performed at the same time. Results the positive rate of T-SPOT.TB in the study group was 80.0, which was significantly higher than that in the control group (13.3%) (蠂 ~ (2) 2) (32.14 / P0.01). The positive rates of T-SPOT.TB in the study group were 13.3% and 6.7%, respectively, and the positive rates of T-SPOT.TB were 86.7% and 76.77% in the patients with CD4 T cell count 鈮，
本文编号：2131595
[Abstract]:Objective to evaluate the clinical value of T cell spot test (T-SPOT.TB) in the diagnosis of AIDS complicated with pulmonary tuberculosis. Methods T-SPOT.TB was detected in 45 AIDS patients with pulmonary tuberculosis (study group) and 30 AIDS patients without pulmonary tuberculosis (control group), and the PPD test was performed at the same time. Results the positive rate of T-SPOT.TB in the study group was 80.0, which was significantly higher than that in the control group (13.3%) (蠂 ~ (2) 2) (32.14 / P0.01). The positive rates of T-SPOT.TB in the study group were 13.3% and 6.7%, respectively, and the positive rates of T-SPOT.TB were 86.7% and 76.77% in the patients with CD4 T cell count 鈮，
本文编号：2131595
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