CAT与mMRC在慢性阻塞性肺疾病临床评价中的价值

发布时间：2018-08-06 20:57

【摘要】：目的应用慢性阻塞性肺疾病(COPD)评估测试量表(CAT)或改良英国医学研究理事会呼吸困难指数(mMRC)分级以及6分钟步行试验(6MWT)评价COPD患者健康状况、呼吸困难程度和运动耐力,并分析其评分结果与COPD患者第1秒用力呼气量占预计值百分比(FEV1%pred)及是否合并肺动脉高压(PH)的相关性。方法对70例确诊COPD患者进行CAT、mMRC评分及6MWT,综合评价评分系统之间以及各评分系统与患者肺功能气流受限严重程度的相关性;对COPD合并PH组与单纯COPD组的CAT、mMRC评分及6分钟步行的距离(6MWD)进行比较。结果CAT评分与6MWD呈负相关(r=-0.623,P0.01),与FEV1%pred无相关性(P=0.159)。CAT与mMRC呈正相关(r=0.492,P=0.000),mMRC与6MWD呈负相关(r=-0.514,P=0.000),与FEV1%pred无相关性(P0.05)。COPD合并PH组与单纯COPD组CAT评分比较,差异有统计学意义(P0.01)。6MWD作为筛查COPD是否合并PH准确性最高,CAT次之。采用CAT判定COPD合并PH风险性的诊断截断点为21。结论 CAT评分与6MWD相关性较好,与FEV1%pred无相关性,CAT评分更适用于整体评价COPD总体严重性,分数高者合并PH可能性大。
[Abstract]:Objective to evaluate the health status, dyspnea and exercise endurance of the patients with chronic obstructive pulmonary disease (COPD) assessment test scale (CAT) or improved British Medical Research Council's respiratory difficulty index (mMRC) and 6 minute walking test (6MWT), and to analyze the score and the estimated 1 second forced expiratory volume in COPD patients. The correlation between the score (FEV1%pred) and the combination of pulmonary hypertension (PH). Methods 70 patients with COPD were treated with CAT, mMRC score and 6MWT. The correlation between the scoring system and the severity of pulmonary function limitation of the patients was evaluated, and the CAT, mMRC score and 6 minute walk of the COPD combined with the PH group and the simple COPD group were evaluated. The CAT score was negatively correlated with 6MWD (r=-0.623, P0.01), and there was no correlation between FEV1%pred (P=0.159) and mMRC (r=0.492, P=0.000), and there was a negative correlation between.CAT and mMRC (r=0.492, P=0.000). The difference was statistically significant compared with that of the 6MWD. 01) the accuracy of.6MWD as a screening COPD for PH was the highest, CAT times. The diagnostic truncation point of COPD with PH risk was determined by CAT. Conclusion the correlation between CAT score and 6MWD was better, and there was no correlation with FEV1%pred. CAT score was more applicable to overall evaluation of the severity of COPD.
【作者单位】：宁夏医科大学临床学院呼吸内科;宁夏医科大学总医院呼吸与危重症医学科;
【基金】：宁夏自然科学基金资助项目(nz11278)
【分类号】：R563.9

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