机械通气患者获得性肺炎与奥美拉唑使用时间的相关性研究

发布时间：2018-08-20 10:09

【摘要】：目的分析机械通气患者获得性肺炎与奥美拉唑使用时间的相关性。方法选择在本院重症监护室(ICU)接受机械性通气治疗的患者作为研究对象,分别接受奥美拉唑治疗3,5,7,15 d,比较各组的胃液pH值,应激性溃疡发生率,呼吸机相关性肺炎发生率,感染发生优势菌群情况,获得性肺炎与奥美拉唑使用时间的相关性情况。结论 3 d,5 d,7 d,15 d组胃液pH值分别为(1.53±0.31),(2.74±0.74),(5.21±1.23),(6.42±1.42);应激性溃疡发生率分别为16.67%,13.33%,10.00%,3.33%;呼吸机相关肺炎发生率分别为26.67%,33.33%,40.00%,46.67%;呼吸机相关性肺炎与应激性溃疡优势菌群符合率高达50%。结论奥美拉唑使用时间与胃液pH值、呼吸机相关性肺炎发生例数呈正相关,与应激性溃疡发生例数呈负相关。
[Abstract]:Objective to analyze the correlation between acquired pneumonia and duration of Omeprazole in patients with mechanical ventilation. Methods the patients treated with mechanical ventilation in intensive care unit (ICU) of our hospital were treated with omeprazole for 3 days and 75 days, respectively. The gastric juice pH value, the incidence of stress ulcer and the incidence of ventilator-associated pneumonia were compared in each group. The prevalence of infection and the correlation between acquired pneumonia and duration of use of omeprazole. Conclusion the pH value of gastric juice was (1.53 卤0.31), (2.74 卤0.74), (5.21 卤1.23), (6.42 卤1.42), the incidence rate of stress ulcer was 16.677.73 卤13.333.33, the incidence of ventilator-associated pneumonia was 26.6733.330.40.0046.677.The coincidence rate between ventilator-associated pneumonia and stress ulcer was 506.670.The gastric juice pH value was (1.53 卤0.31), (卤0.74), (5.21 卤1.23), (6.42 卤1.42; the incidence of ventilator associated pneumonia was 26.6733.333.40.0046.670.The coincidence rate between ventilator associated pneumonia and stress ulcer was as high as 506.67%. Conclusion the use time of omeprazole was positively correlated with the pH value of gastric juice and the number of ventilator-associated pneumonia cases, and negatively correlated with the number of stress ulcer cases.
【作者单位】：杭州师范大学附属医院重症医学;
【分类号】：R563.1

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