脉冲振荡技术评价尘肺患者肺功能的应用价值
发布时间：2018-10-09 08:26
【摘要】：目的探讨脉冲振荡肺功能(IOS)评价尘肺患者肺功能的临床价值。方法对119例尘肺患者和79例健康者依次进行IOS及PFT检测,分析两组人群两种肺功能各项指标之间的差异、相关性。结果对于早期(壹期)尘肺组,PFT中FEV1、FVC、FEV1/FVC、MVV较健康对照组无明显差异,MEF25、MEF50、MEF75则明显降低,差异有统计学意义(P0.05);而IOS参数中Z5、X5、AX明显升高,差异有统计学意义(P0.05)。在PFT正常的尘肺患者中,壹期尘肺组的IOS参数较健康对照组无明显差异,而贰叁期尘肺组的Z5、X5、Fres则明显升高,差异有统计学意义(P0.05);壹期尘肺组和贰叁期尘肺组IOS异常率均较PFT高,差异有统计学意义(P0.05);IOS参数Z5、R5、R20、R5-R20、Fres、AX与PFT指标FVC、FEVl、FEVl/FVC、MVV、MEF25、MEF50、MEF75呈负相关,X5则呈正相关,两种肺功能指标相关系数(绝对值)按由高到低依次为:Fres与FEV1/FVC(r=-0.566)、Fres与FEVl(r=-0.557)、Z5与FEVl/FVC(r=-0.544)、AX与FEVl/FVC(r=-0.541)、R5与FEVl/FVC(r=-0.541),在贰叁期尘肺组中相关性更高。结论 IOS可以发现早期尘肺患者的气道阻力异常,其操作简便、对受检者配合度要求低,可能是尘肺患者肺功能评价的有益补充。
[Abstract]:Objective to evaluate the clinical value of pulsed oscillatory pulmonary function (IOS) in evaluating pulmonary function in patients with pneumoconiosis. Methods IOS and PFT were detected in 119 patients with pneumoconiosis and 79 healthy subjects respectively. The difference and correlation between the two indexes of pulmonary function were analyzed. Results there was no significant difference in FEV1,FVC,FEV1/FVC,MVV between the early stage and the control group (P 0.05), but there was a significant difference between the two groups (P0.05), while the IOS parameter of Z5F5AX was significantly higher than that of the control group (P0.05). In PFT normal pneumoconiosis patients, the IOS parameters of stage 1 pneumoconiosis group were not significantly different from those of healthy control group, but Z5 X 5 Fres level of stage 223 pneumoconiosis group was significantly higher than that of control group (P0.05), the abnormal rate of IOS in stage 1 pneumoconiosis group and stage 23 pneumoconiosis group was higher than that in PFT group. 宸紓鏈夌粺璁″鎰忎箟(P0.05);IOS鍙傛暟Z5,R5,R20,R5-R20,Fres,AX涓嶱FT鎸囨爣FVC,FEVl,FEVl/FVC,MVV,MEF25,MEF50,MEF75鍛堣礋鐩稿叧,X5鍒欏憟姝ｇ浉鍏，
本文编号：2258658
[Abstract]:Objective to evaluate the clinical value of pulsed oscillatory pulmonary function (IOS) in evaluating pulmonary function in patients with pneumoconiosis. Methods IOS and PFT were detected in 119 patients with pneumoconiosis and 79 healthy subjects respectively. The difference and correlation between the two indexes of pulmonary function were analyzed. Results there was no significant difference in FEV1,FVC,FEV1/FVC,MVV between the early stage and the control group (P 0.05), but there was a significant difference between the two groups (P0.05), while the IOS parameter of Z5F5AX was significantly higher than that of the control group (P0.05). In PFT normal pneumoconiosis patients, the IOS parameters of stage 1 pneumoconiosis group were not significantly different from those of healthy control group, but Z5 X 5 Fres level of stage 223 pneumoconiosis group was significantly higher than that of control group (P0.05), the abnormal rate of IOS in stage 1 pneumoconiosis group and stage 23 pneumoconiosis group was higher than that in PFT group. 宸紓鏈夌粺璁″鎰忎箟(P0.05);IOS鍙傛暟Z5,R5,R20,R5-R20,Fres,AX涓嶱FT鎸囨爣FVC,FEVl,FEVl/FVC,MVV,MEF25,MEF50,MEF75鍛堣礋鐩稿叧,X5鍒欏憟姝ｇ浉鍏，
本文编号：2258658
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